| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4817667 | Binding | Inhibition of BACE1 (unknown origin) by HTRF assay | Homo sapiens | 8 | ALA4814016 | single protein format | Scientific Literature | |
| 2. | ALA4817668 | Binding | Inhibition of BACE1 in human SH-SY5Y cells expressing APP assessed as reduction in Abeta40 by HTRF assay | Homo sapiens | 8 | ALA4814016 | cell-based format | Scientific Literature | |
| 3. | ALA4817669 | Physicochemical | Dissociation constant, pKa of compound by capillary electrophoresis | 8 | ALA4814016 | small-molecule physicochemical format | Scientific Literature | ||
| 4. | ALA4817670 | ADME | Substrate activity at P-gp (unknown origin) transfected in LLC-PK1 cells expressing human MDR1 gene assessed as efflux ratio | Homo sapiens | 3 | ALA4814016 | cell-based format | Scientific Literature | |
| 5. | ALA4817671 | Binding | Inhibition of human ERG at 5 uM by automated patch clamp assay relative to control | Homo sapiens | 5 | ALA4814016 | assay format | Scientific Literature | |
| 6. | ALA4817672 | ADME | Metabolic stability in rat liver microsomes assessed as parent compound remaining measured after 30 mins | Rattus norvegicus | 1 | ALA4814016 | microsome format | Scientific Literature | |
| 7. | ALA4817673 | ADME | Fraction unbound in rat serum | Rattus norvegicus | 1 | ALA4814016 | cell-free format | Scientific Literature | |
| 8. | ALA4817674 | ADME | Clearance in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | ALA4814016 | organism-based format | Scientific Literature | |
| 9. | ALA4817675 | ADME | Volume of distribution at steady state in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | ALA4814016 | organism-based format | Scientific Literature | |
| 10. | ALA4817676 | ADME | Ratio of drug level in brain to plasma in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | ALA4814016 | organism-based format | Scientific Literature | |
| 11. | ALA4817677 | ADME | AUC in rat at 1 mg/kg, po | Rattus norvegicus | 1 | ALA4814016 | organism-based format | Scientific Literature | |
| 12. | ALA4817678 | ADME | Cmax in rat at 1 mg/kg, po | Rattus norvegicus | 1 | ALA4814016 | organism-based format | Scientific Literature | |
| 13. | ALA4817679 | ADME | Tmax in rat at 1 mg/kg, po | Rattus norvegicus | 1 | ALA4814016 | organism-based format | Scientific Literature | |
| 14. | ALA4817680 | ADME | Oral bioavailability in rat at 1 mg/kg | Rattus norvegicus | 1 | ALA4814016 | organism-based format | Scientific Literature | |
| 15. | ALA4817681 | ADME | Metabolic stability in Beagle dog liver microsomes assessed as parent compound remaining measured after 30 mins | Canis lupus familiaris | 1 | ALA4814016 | microsome format | Scientific Literature | |
| 16. | ALA4817682 | ADME | Fraction unbound in Beagle dog serum | Canis lupus familiaris | 1 | ALA4814016 | cell-free format | Scientific Literature | |
| 17. | ALA4817683 | ADME | Clearance in Beagle dog at 0.5 mg/kg, iv | Canis lupus familiaris | 1 | ALA4814016 | organism-based format | Scientific Literature | |
| 18. | ALA4817684 | ADME | Volume of distribution at steady state in Beagle dog at 0.5 mg/kg, iv | Canis lupus familiaris | 1 | ALA4814016 | organism-based format | Scientific Literature | |
| 19. | ALA4817685 | ADME | Ratio of drug level in brain to plasma in Beagle dog at 0.5 mg/kg, iv | Canis lupus familiaris | 1 | ALA4814016 | organism-based format | Scientific Literature | |
| 20. | ALA4817686 | ADME | AUC in Beagle dog at 3 mg/kg, po | Canis lupus familiaris | 1 | ALA4814016 | organism-based format | Scientific Literature |
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