| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4815375 | Functional | Immunosuppressive activity in BALB/c mouse splenocytes assessed as inhibition of concanavalin A-stimulated T-cell proliferation incubated for 48 hrs by MTT assay | Mus musculus | 21 | ALA4813949 | cell-based format | Scientific Literature | |
| 2. | ALA4815376 | Functional | Immunosuppressive activity in BALB/c mouse splenocytes assessed as inhibition of LPS-stimulated B-cell proliferation incubated for 48 hrs by MTT assay | Mus musculus | 21 | ALA4813949 | cell-based format | Scientific Literature | |
| 3. | ALA4815377 | ADME | Cytotoxicity against BALB/c mouse splenocytes at 50 uM incubated for 48 hrs by MTT assay | Mus musculus | 19 | ALA4813949 | cell-based format | Scientific Literature | |
| 4. | ALA4815378 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as early apoptotic cells at 5 uM after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 6.9 %) | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature | |
| 5. | ALA4815379 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as late apoptotic cells at 5 uM after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 0.4 %) | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature | |
| 6. | ALA4815380 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as early apoptotic cells at 10 uM after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 6.9 %) | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature | |
| 7. | ALA4815381 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as late apoptotic cells at 10 uM after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 0.4 %) | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature | |
| 8. | ALA4815382 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as early apoptotic cells at 20 uM after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 6.9 %) | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature | |
| 9. | ALA4815383 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as late apoptotic cells at 20 uM after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 0.4 %) | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature | |
| 10. | ALA4815390 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as increase in Bax protein expression after 48 hrs by Western blotting analysis | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature | |
| 11. | ALA4815391 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as increase in cytochrome C protein expression after 48 hrs by Western blotting analysis | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature | |
| 12. | ALA4815392 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as increase in cleaved caspase 3 protein expression after 48 hrs by Western blotting analysis | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature | |
| 13. | ALA4815393 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as increase in cleaved caspase 9 protein expression after 48 hrs by Western blotting analysis | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature | |
| 14. | ALA4815394 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as decrease in Bcl-2 protein expression after 48 hrs by Western blotting analysis | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature | |
| 15. | ALA4815395 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as decrease in Mcl-1 protein expression after 48 hrs by Western blotting analysis | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature | |
| 16. | ALA4815396 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as decrease in Bcl-xL protein expression after 48 hrs by Western blotting analysis | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature | |
| 17. | ALA4815397 | Functional | Induction of apoptosis in ConA-induced mouse splenic T cells assessed as downregulation of JNK phosphorylation after 48 hrs by Western blotting analysis | Mus musculus | 1 | ALA4813949 | cell-based format | Scientific Literature |
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