| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4826128 | F | Antiproliferative activity against human PC-9 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA4826129 | F | Antiproliferative activity against human PB1 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA4826130 | F | Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA4826131 | F | Antiproliferative activity against human HCC827 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 5. | ALA4826132 | F | Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 6. | ALA4826133 | F | Antiproliferative activity against mouse BaF3 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Mus musculus | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA4826134 | A | Cytotoxicity against human HEK293T cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA4826135 | A | Cytotoxicity against human BJ cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 9. | ALA4826136 | B | Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation measured after 16 hrs by Western blot assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4826137 | B | Protac activity at CRBN/EGFR in human PC-9 cells assessed as induction of EGFR degradation by Western blot assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 11. | ALA4826138 | B | Protac activity at CRBN/EGFR in human PB1 cells assessed as induction of EGFR degradation by Western blot assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 12. | ALA4826139 | B | Protac activity at CRBN/EGFR in human NCI-H1975 cells assessed as induction of EGFR degradation by Western blot assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 13. | ALA4826140 | B | Protac activity at CRBN/EGFR in human A549 cells assessed as induction of EGFR degradation by Western blot assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 14. | ALA4826141 | B | Protac activity at CRBN/EGFR in mouse BaF3 cells assessed as induction of EGFR degradation by Western blot assay | Mus musculus | 8 | cell-based format | Scientific Literature | ||
| 15. | ALA4826142 | B | Protac activity at CRBN/EGFR exon 19 deletion mutant in human PC-9 cells assessed as induction of EGFR degradation at >10 nM measured after 48 hrs by Western blot assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4826143 | B | Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation at 50 nM measured after 16 hrs by Western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4826145 | B | Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation measured after 48 hrs by Western blot assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4826146 | B | Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation at 300 nM measured after 8 to 72 hrs by Western blot assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4826147 | B | Protac activity at CRBN/EGFR exon19 deletion/T790M mutant in human PC-9 cells transfected with BRCA1 assessed as induction of EGFR degradation at 1 to 1000 nM measured after 16 hrs by Western blot assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA4826148 | B | Protac activity at CRBN/EGFR exon19 deletion/T790M mutant in human PC-9 cells transfected with BRCA1 assessed as induction of EGFR degradation at 1 to 1000 nM measured after 48 hrs by Western blot assay | Homo sapiens | 2 | cell-based format | Scientific Literature |
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