# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4832929 | B | Protac activity at IAP/RIPK2 in human whole blood assessed as inhibition of MDP-induced TNFalpha production by ELISA | Homo sapiens | 20 | tissue-based format | Scientific Literature | ||
2. | ALA4832931 | P | Lipophilicity, logD of compound at pH 7.4 by Chromatography | 20 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA4832937 | A | Clearance in Sprague-Dawley rat at 2 mg/kg, iv administered as single dose | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
4. | ALA4832938 | A | Half life in Sprague-Dawley rat at 2 mg/kg, iv administered as single dose | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
5. | ALA4832939 | A | Volume of distribution at steady state in Sprague-Dawley rat at 2 mg/kg, iv administered as single dose | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
6. | ALA4832944 | B | Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive ligand by fluorescent polarization based binding assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
7. | ALA4832949 | B | Binding affinity to human His-thr XIAP BIR2 (124 to 240) domain expressed in Escherichia coli measured after 105 mins in dark by time-resolved fluorescence laser-equipped multimode plate reader | Homo sapiens | 3 | assay format | Scientific Literature | ||
8. | ALA4832950 | B | Binding affinity to human His-thr XIAP BIR3 (241 to 356) domain expressed in Escherichia coli measured after 105 mins in dark by time-resolved fluorescence laser-equipped multimode plate reader | Homo sapiens | 3 | assay format | Scientific Literature | ||
9. | ALA4832951 | B | Binding affinity to human 6His-thr cIAP1 BIR3 (253 to 363) domain expressed in Escherichia coli measured after 105 mins in dark by time-resolved fluorescence laser-equipped multimode plate reader | Homo sapiens | 3 | assay format | Scientific Literature |