# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4841939 | F | Antiviral activity against HIV-1 infected in MT4 cells assessed as reduction in virus-induced cytopathic effect preincubated for 1 hr followed by viral infection and measured after 5 days by XTT assay | Human immunodeficiency virus 1 | 51 | ALA4840358 | organism-based format | Scientific Literature | |
2. | ALA4841940 | A | Cytotoxicity against in human MT4 cells after 5 days by XTT assay | Homo sapiens | 51 | ALA4840358 | cell-based format | Scientific Literature | |
3. | ALA4841950 | B | Substrate activity at cathepsin A (unknown origin) at 30 uM after 30 mins | Homo sapiens | 9 | ALA4840358 | single protein format | Scientific Literature | |
4. | ALA4841951 | A | Drug uptake in human CCRF-CEM cells assessed as intracellular intact prodrug level at 50 uM after 45 mins by ECHO-MS analysis | Homo sapiens | 9 | ALA4840358 | cell-based format | Scientific Literature | |
5. | ALA4841952 | A | Drug uptake in human CCRF-CEM cells assessed as released tenofovir level at 50 uM after 45 mins by ECHO-MS analysis | Homo sapiens | 9 | ALA4840358 | cell-based format | Scientific Literature | |
6. | ALA4841953 | A | Drug metabolism assessed as M1 metabolite formation | 1 | ALA4840358 | assay format | Scientific Literature | ||
7. | ALA4841956 | A | Drug metabolism assessed as M4 metabolite formation | 1 | ALA4840358 | assay format | Scientific Literature | ||
8. | ALA4841957 | A | Drug metabolism assessed as M5 metabolite formation | 1 | ALA4840358 | assay format | Scientific Literature | ||
9. | ALA4841958 | A | Drug metabolism assessed as M6 metabolite formation | 1 | ALA4840358 | assay format | Scientific Literature | ||
10. | ALA4841959 | A | Drug metabolism assessed as M7 metabolite formation | 1 | ALA4840358 | assay format | Scientific Literature | ||
11. | ALA4841960 | A | Drug metabolism assessed as M8 metabolite formation | 1 | ALA4840358 | assay format | Scientific Literature | ||
12. | ALA4841961 | A | Drug metabolism assessed as M9 metabolite formation | 1 | ALA4840358 | assay format | Scientific Literature | ||
13. | ALA4841962 | A | Drug metabolism assessed as M10 metabolite formation | 1 | ALA4840358 | assay format | Scientific Literature | ||
14. | ALA4841963 | A | Drug metabolism assessed as M11 metabolite formation | 1 | ALA4840358 | assay format | Scientific Literature | ||
15. | ALA4841964 | A | Drug metabolism assessed as M12 metabolite formation | 1 | ALA4840358 | assay format | Scientific Literature |