# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4813043 | Functional | Antiviral activity against Zika virus infected in human SF-268 cells assessed as inhibition of virus-induced cytopathic effect at 10 uM measured at 96 hrs MTT assay | Zika virus | 11 | ALA4811277 | organism-based format | Scientific Literature | |
2. | ALA4813044 | Functional | Antiviral activity against Zika virus infected in human SF-268 cells assessed as reduction in viral NS1 protein synthesis at 10 uM measured at 96 hrs by immunofluorescence assay relative to control | Zika virus | 11 | ALA4811277 | organism-based format | Scientific Literature | |
3. | ALA4813045 | ADME | Cytotoxicity against human SF-268 cells assessed as inhibition of cell viability measured after 96 hrs by MTT assay | Homo sapiens | 11 | ALA4811277 | cell-based format | Scientific Literature | |
4. | ALA4813046 | Functional | Antiviral activity against Zika virus infected in human SF-268 cells assessed as reduction in viral infection by DAPI staining based immunofluorescence assay | Zika virus | 11 | ALA4811277 | organism-based format | Scientific Literature | |
5. | ALA4813047 | Toxicity | Therapeutic index, ratio of CC50 for cytotoxicity against human SF-268 cells to IC50 for antiviral activity against Zika virus infected in human SF-268 cells | 11 | ALA4811277 | cell-based format | Scientific Literature | ||
6. | ALA4813048 | Functional | Antiviral activity against Zika virus infected in SF-268 cells assessed as inhibition of viral infection at entry stage measured after 96 hrs by DAPI staining based fluorescence microscopic analysis | Zika virus | 4 | ALA4811277 | organism-based format | Scientific Literature | |
7. | ALA4813049 | Functional | Antiviral activity against Zika virus infected in SF-268 cells assessed as inhibition of viral infection at post entry stage after 96 hrs measured after 1 hr post infection by DAPI staining based fluorescence microscopic analysis | Zika virus | 4 | ALA4811277 | organism-based format | Scientific Literature |