#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4843234	Binding	Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysis	Mus musculus	7	ALA4842341	cell-based format	Scientific Literature
2.	ALA4843236	Binding	Inhibition of recombinant human His-tagged IDO1 (Ala2 to Gly403 residues) expressed in Escherichia coli using tryptophan as substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by RFMS assay	Homo sapiens	12	ALA4842341	assay format	Scientific Literature
3.	ALA4843237	Binding	Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assay	Homo sapiens	62	ALA4842341	cell-based format	Scientific Literature
4.	ALA4843238	ADME	Intrinsic clearance in rat liver microsomes at 1 uM measured up to 45 mins in presence of NADPH by LC-MS/MS analysis	Rattus norvegicus	12	ALA4842341	microsome format	Scientific Literature
5.	ALA4843239	ADME	Intrinsic clearance in human liver microsomes at 1 uM measured up to 45 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	48	ALA4842341	microsome format	Scientific Literature
6.	ALA4843244	ADME	Clearance in CD-1 mouse at 0.3 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis	Mus musculus	7	ALA4842341	organism-based format	Scientific Literature
7.	ALA4843245	ADME	Volume of distribution at steady state in CD-1 mouse at 0.3 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis	Mus musculus	7	ALA4842341	organism-based format	Scientific Literature
8.	ALA4843246	ADME	Terminal half life in CD-1 mouse at 0.3 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis	Mus musculus	7	ALA4842341	organism-based format	Scientific Literature
9.	ALA4843247	ADME	AUC (0 to infinity) in CD-1 mouse at 0.3 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis	Mus musculus	7	ALA4842341	organism-based format	Scientific Literature
10.	ALA4843248	ADME	Cmax in CD-1 mouse at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis	Mus musculus	7	ALA4842341	organism-based format	Scientific Literature
11.	ALA4843249	ADME	Oral bioavailability in CD-1 mouse at 10 mg/kg measured upto 24 hrs by LC-MS/MS analysis	Mus musculus	7	ALA4842341	organism-based format	Scientific Literature
12.	ALA4843251	Binding	Selectivity ratio of IC50 for inhibition of human ERG by fluorescence polarization method to IC50 for inhibition of IDO1 in human HeLa cells	Homo sapiens	4	ALA4842341	cell-based format	Scientific Literature
13.	ALA4843252	Binding	Inhibition of human ERG by Qpatch method	Homo sapiens	3	ALA4842341	single protein format	Scientific Literature
14.	ALA4843259	Functional	In vivo inhibition of IDO1 in Balb/c mouse assessed as KYN level	Mus musculus	4	ALA4842341	organism-based format	Scientific Literature
15.	ALA4843280	ADME	Inhibition of CYP2C9 in human liver microsomes using sulfaphenazole as substrate incubated for 10 mins in presence of NADPH by LCMS/MS analysis	Homo sapiens	27	ALA4842341	microsome format	Scientific Literature
16.	ALA4843292	ADME	Drug concentration in tumor of NSG mouse xenografted with human SKOV3 cells at 125 mg/kg, po BID administered for 5 days and measured 24 hrs post dose	Mus musculus	3	ALA4842341	organism-based format	Scientific Literature
17.	ALA4843296	ADME	Drug concentration in plasma of NSG mouse xenografted with human SKOV3 cells at 125 mg/kg, po BID administered for 5 days and measured 24 hrs post dose	Mus musculus	3	ALA4842341	organism-based format	Scientific Literature
18.	ALA4843301	ADME	Protein binding in mouse plasma at 5 uM incubated for 5 hrs by rapid equilibrium dialysis based LC-MS/MS analysis	Mus musculus	13	ALA4842341	cell-free format	Scientific Literature
19.	ALA4843302	Functional	In vivo inhibition of IDO1 in tumor of NSG mouse xenografted with human SKOV3 cells assessed as KYN level at 125 mg/kg, po BID administered for 5 days and measured 24 hrs post dose	Mus musculus	3	ALA4842341	organism-based format	Scientific Literature