#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4832446	Binding	Displacement of [3H]-DPN from mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1 hr by radioligand competition binding based assay	Mus musculus	2	ALA4831505	cell membrane format	Scientific Literature
2.	ALA4832447	Functional	Agonist activity at mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring maximum efficacy incubated for 30 mins by HTRF assay relative to control	Mus musculus	2	ALA4831505	cell membrane format	Scientific Literature
3.	ALA4832448	Functional	Agonist activity at mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production incubated for 30 mins by HTRF assay	Mus musculus	2	ALA4831505	cell membrane format	Scientific Literature
4.	ALA4832449	Functional	Agonist activity at mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as beta-arrestin 2 recruitment up to 100 uM using furimazine as a substrate preincubated for 5 mins followed by ligand addition measured for 35 mins by BRET assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
5.	ALA4832452	Binding	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1-13 to orthosteric binding site at 0.03 uM coincubated with dyn A1-13 for 90 mins by radioligand competition binding assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
6.	ALA4832453	Binding	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1-13 to orthosteric binding site at 0.1 uM coincubated with dyn A1-13 for 90 mins by radioligand competition binding assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
7.	ALA4832454	Binding	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1-13 to orthosteric binding site at 0.3 uM coincubated with dyn A1-13 for 90 mins by radioligand competition binding assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
8.	ALA4832455	Binding	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1-13 to orthosteric binding site at 1 uM coincubated with dyn A1-13 for 90 mins by radioligand competition binding assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
9.	ALA4832456	Binding	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1-13 to orthosteric binding site at 3 uM coincubated with dyn A1-13 for 90 mins by radioligand competition binding assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
10.	ALA4832457	Binding	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1-13 to orthosteric binding site at 10 uM coincubated with dyn A1-13 for 90 mins by radioligand competition binding assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
11.	ALA4832458	Binding	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1-13 to orthosteric binding site at 30 uM coincubated with dyn A1-13 for 90 mins by radioligand competition binding assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
12.	ALA4832460	Functional	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring dyn A1-13 EC50 at 0.03 uM pretreated for 30 mins followed by coincubation with dyn A1-13 measured after 30 mins by HTRF assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
13.	ALA4832461	Functional	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring dyn A1-13 EC50 at 0.1 uM pretreated for 30 mins followed by coincubation with dyn A1-13 measured after 30 mins by HTRF assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
14.	ALA4832462	Functional	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring dyn A1-13 EC50 at 0.3 uM pretreated for 30 mins followed by coincubation with dyn A1-13 measured after 30 mins by HTRF assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
15.	ALA4832463	Functional	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring dyn A1-13 EC50 at 1 uM pretreated for 30 mins followed by coincubation with dyn A1-13 measured after 30 mins by HTRF assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
16.	ALA4832464	Functional	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring dyn A1-13 EC50 at 3 uM pretreated for 30 mins followed by coincubation with dyn A1-13 measured after 30 mins by HTRF assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
17.	ALA4832465	Functional	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring dyn A1-13 EC50 at 10 uM pretreated for 30 mins followed by coincubation with dyn A1-13 measured after 30 mins by HTRF assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
18.	ALA4832466	Functional	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring dyn A1-13 EC50 at 30 uM pretreated for 30 mins followed by coincubation with dyn A1-13 measured after 30 mins by HTRF assay	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
19.	ALA4832468	Functional	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring dyn A1-13 Emax at 0.03 uM pretreated for 30 mins followed by coincubation with dyn A1-13 measured after 30 mins by HTRF assay relative to control	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature
20.	ALA4832469	Functional	Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring dyn A1-13 Emax at 0.1 uM pretreated for 30 mins followed by coincubation with dyn A1-13 measured after 30 mins by HTRF assay relative to control	Mus musculus	1	ALA4831505	cell membrane format	Scientific Literature