| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4843081 | Functional | Antiproliferative activity against human BEAS-2B cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 12 | ALA4842337 | cell-based format | Scientific Literature | |
| 2. | ALA4843082 | Functional | Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 12 | ALA4842337 | cell-based format | Scientific Literature | |
| 3. | ALA4843083 | ADME | Cytotoxicity against human L02 cells assessed as cell viability measured after 72 hrs by MTT assay | Homo sapiens | 12 | ALA4842337 | cell-based format | Scientific Literature | |
| 4. | ALA4843084 | Functional | Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 12 | ALA4842337 | cell-based format | Scientific Literature | |
| 5. | ALA4843085 | Functional | Antiproliferative activity against human HePAD38 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 9 | ALA4842337 | cell-based format | Scientific Literature | |
| 6. | ALA4843086 | Unassigned | Selectivity index, ratio of IC50 for human L02 cells to IC50 for human HePAD38 cells | Homo sapiens | 7 | ALA4842337 | assay format | Scientific Literature | |
| 7. | ALA4843087 | Unassigned | Selectivity index, ratio of IC50 for human CCD 19Lu cells to IC50 for human HePAD38 cells | Homo sapiens | 7 | ALA4842337 | assay format | Scientific Literature | |
| 8. | ALA4843088 | Toxicity | Selectivity index, ratio of IC50 for human L02 cells to IC50 for human HepG2 cells | Homo sapiens | 7 | ALA4842337 | assay format | Scientific Literature | |
| 9. | ALA4843089 | Toxicity | Selectivity index, ratio of IC50 for human CCD 19Lu cells to IC50 for human HepG2 cells | Homo sapiens | 7 | ALA4842337 | assay format | Scientific Literature | |
| 10. | ALA4843091 | Binding | Inhibition of P-gp in human A549/Taxol cells assessed as increase in rhodamine 123 accumulation at 0.5 uM preincubated for 4 hrs followed by addition of rhodamine 123 and measured after 1 hr by flow cytometry assay (Rvb = 26.5%) | Homo sapiens | 3 | ALA4842337 | cell-based format | Scientific Literature | |
| 11. | ALA4843092 | Binding | Inhibition of human SERCA in human HeLa cells assessed as alteration of calcium dynamics at 1 uM measured by FLIPR calcium assay | Homo sapiens | 3 | ALA4842337 | cell-based format | Scientific Literature | |
| 12. | ALA4843093 | Binding | Inhibition of human SERCA in human HeLa cells assessed as depletion of SERCA-dependent calcium storage at 1 uM preincubated with TG by FLIPR calcium assay | Homo sapiens | 3 | ALA4842337 | cell-based format | Scientific Literature | |
| 13. | ALA4843094 | Binding | Inhibition of human SERCA in human HeLa cells assessed as alteration of calcium dynamics at 1 uM preincubated with compound C measured after 2 hrs by FLIPR calcium assay | Homo sapiens | 3 | ALA4842337 | cell-based format | Scientific Literature | |
| 14. | ALA4843095 | ADME | Induction of apoptosis in human L02 cells assessed as viable cells at 1 uM measured after 24 hrs by Annexin-V/PI staining based flow cytometry assay (Rvb = 97.5%) | Homo sapiens | 3 | ALA4842337 | cell-based format | Scientific Literature | |
| 15. | ALA4843096 | ADME | Induction of apoptosis in human L02 cells assessed as early apoptotic cells at 1 uM measured after 24 hrs by Annexin-V/PI staining based flow cytometry assay (Rvb = 1.49%) | Homo sapiens | 3 | ALA4842337 | cell-based format | Scientific Literature | |
| 16. | ALA4843097 | ADME | Induction of apoptosis in human L02 cells assessed as late apoptotic cells at 1 uM measured after 24 hrs by Annexin-V/PI staining based flow cytometry assay (Rvb = 0.133%) | Homo sapiens | 3 | ALA4842337 | cell-based format | Scientific Literature | |
| 17. | ALA4843098 | ADME | Induction of apoptosis in human L02 cells assessed as necrotic cells at 1 uM measured after 24 hrs by Annexin-V/PI staining based flow cytometry assay (Rvb = 0.848%) | Homo sapiens | 3 | ALA4842337 | cell-based format | Scientific Literature | |
| 18. | ALA4843099 | Functional | Induction of apoptosis in human HepG2 cells assessed as viable cells at 1 uM measured after 24 hrs by Annexin-V/PI staining based flow cytometry assay (Rvb = 99.1%) | Homo sapiens | 3 | ALA4842337 | cell-based format | Scientific Literature | |
| 19. | ALA4843100 | Functional | Induction of apoptosis in human HepG2 cells assessed as early apoptotic cells at 1 uM measured after 24 hrs by Annexin-V/PI staining based flow cytometry assay (Rvb = 0.181%) | Homo sapiens | 3 | ALA4842337 | cell-based format | Scientific Literature | |
| 20. | ALA4843101 | Functional | Induction of apoptosis in human HepG2 cells assessed as late apoptotic cells at 1 uM measured after 24 hrs by Annexin-V/PI staining based flow cytometry assay (Rvb = 0.016%) | Homo sapiens | 3 | ALA4842337 | cell-based format | Scientific Literature |
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