| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4831058 | Binding | Negative modulator activity at human TLR8 expressed in HEK-Blue hTLR8 cells assessed as inhibition of TL8-506 stimulated NF-kappaB activation preincubated with compound for 1 hr followed by TL8-506 stimulation for 24 hrs by SEAP-based colorimetric assay | Homo sapiens | 41 | ALA4828757 | cell-based format | Scientific Literature | |
| 2. | ALA4831060 | Binding | Agonist activity at human TLR8 expressed in HEK-Blue hTLR8 cells assessed as NF-kappaB activation at 10 to 25 uM measured after 24 hrs by SEAP-based colorimetric assay | Homo sapiens | 42 | ALA4828757 | cell-based format | Scientific Literature |
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