# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4841562 | Functional | Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by GloSensor cAMP Assay | Homo sapiens | 25 | ALA4840347 | cell-based format | Scientific Literature | |
2. | ALA4841563 | Binding | Inhibition of human ERG expressed in CHO-K1 cells with holding potential -80 mV incubated for 5 mins by patch-clamp assay | Homo sapiens | 22 | ALA4840347 | cell-based format | Scientific Literature | |
3. | ALA4841564 | ADME | Induction of phospholipidosis in CHL/IU cells assessed as intracellular accumulation of phospholipids by fluorescence plate reader assay | Cricetulus griseus | 24 | ALA4840347 | cell-based format | Scientific Literature | |
4. | ALA4841565 | ADME | Cmax in rat at 3 mg/kg, po | Rattus norvegicus | 2 | ALA4840347 | organism-based format | Scientific Literature | |
5. | ALA4841566 | ADME | Tmax in rat at 3 mg/kg, po | Rattus norvegicus | 2 | ALA4840347 | organism-based format | Scientific Literature | |
6. | ALA4841567 | ADME | AUC (0 to 24 hrs) in rat at 1 mg/kg, iv | Rattus norvegicus | 2 | ALA4840347 | organism-based format | Scientific Literature | |
7. | ALA4841568 | ADME | AUC (0 to 24 hrs) in rat at 3 mg/kg, po | Rattus norvegicus | 2 | ALA4840347 | organism-based format | Scientific Literature | |
8. | ALA4841569 | ADME | Half life in rat at 1 mg/kg, iv | Rattus norvegicus | 2 | ALA4840347 | organism-based format | Scientific Literature | |
9. | ALA4841570 | ADME | Half life in rat at 3 mg/kg, po | Rattus norvegicus | 2 | ALA4840347 | organism-based format | Scientific Literature | |
10. | ALA4841571 | ADME | Total clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 2 | ALA4840347 | organism-based format | Scientific Literature | |
11. | ALA4841572 | ADME | Volume of distribution in rat at 1 mg/kg, iv | Rattus norvegicus | 2 | ALA4840347 | organism-based format | Scientific Literature | |
12. | ALA4841573 | ADME | Oral bioavailability in rat at 3 mg/kg | Rattus norvegicus | 1 | ALA4840347 | organism-based format | Scientific Literature | |
13. | ALA4841574 | ADME | Half life in rat liver microsomes measured up to 60 mins in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 2 | ALA4840347 | microsome format | Scientific Literature | |
14. | ALA4841575 | ADME | Permeability of compound by PAMPA assay | 2 | ALA4840347 | assay format | Scientific Literature |