# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4810778 | Functional | Neuroprotective effect against amyloid beta-induced cytotoxicity in mouse N2a cells assessed as cell viability measured after 3 hrs by MTT assay (Rvb = 55%) | Mus musculus | 2 | ALA4808231 | cell-based format | Scientific Literature | |
2. | ALA4810779 | Binding | Inhibition of human amyloid beta 42 aggregation assessed as decreasing in fluorescence intensity for 3 hrs by ThT fluorescence assay | Homo sapiens | 13 | ALA4808231 | assay format | Scientific Literature | |
3. | ALA4810780 | ADME | Neurotoxicity in mouse N2a cells assessed as cell viability for 24 hrs by MTT assay | Mus musculus | 4 | ALA4808231 | cell-based format | Scientific Literature | |
4. | ALA4810781 | ADME | Neurotoxicity in human U87 MG cells assessed as cell viability for 24 hrs by MTT assay | Homo sapiens | 4 | ALA4808231 | cell-based format | Scientific Literature | |
5. | ALA4810782 | Binding | Inhibition of amyloid beta (unknown origin) aggregation assessed as fibril formation at 10 uM incubated for 30 mins by negative staining TEM imaging analysis | Homo sapiens | 1 | ALA4808231 | single protein format | Scientific Literature | |
6. | ALA4810783 | Binding | Inhibition of amyloid beta (unknown origin) aggregation assessed as increase in generation of amyloid beta oligomers at 10 uM incubated for 30 mins by negative staining TEM imaging analysis | Homo sapiens | 1 | ALA4808231 | single protein format | Scientific Literature |