# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4843953 | Binding | Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence method | Schistosoma mansoni | 37 | ALA4842354 | single protein format | Scientific Literature | |
2. | ALA4843955 | Binding | Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assay | Homo sapiens | 25 | ALA4842354 | single protein format | Scientific Literature | |
3. | ALA4843957 | ADME | Inhibition of recombinant human HDAC1 using ZMAL as substrate incubated for 90 mins by fluorescence based micro plate assay | Homo sapiens | 11 | ALA4842354 | single protein format | Scientific Literature | |
4. | ALA4843961 | ADME | Inhibition of recombinant human HDAC6 using ZMAL as substrate incubated for 90 mins by fluorescence based micro plate assay | Homo sapiens | 12 | ALA4842354 | single protein format | Scientific Literature | |
5. | ALA4843965 | Functional | Antischistosomal activity against Schistosoma mansoni schistosomula at 10 uM incubated for 48 hrs by Alamar Blue assay | Schistosoma mansoni | 37 | ALA4842354 | organism-based format | Scientific Literature | |
6. | ALA4843966 | Functional | Antischistosomal activity against Schistosoma mansoni schistosomula at 20 uM incubated for 48 hrs by Alamar Blue assay | Schistosoma mansoni | 37 | ALA4842354 | organism-based format | Scientific Literature | |
7. | ALA4843967 | ADME | Cytotoxicity against human HEK293 assessed as reduction in cell viability at 50 uM measured for 24 hrs by Alamar Blue assay | Homo sapiens | 37 | ALA4842354 | cell-based format | Scientific Literature |