# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4825196 | Binding | Inhibition of human ALDH1A1 assessed as NADH formation using propionaldehyde as substrate by spectrophotometry | Homo sapiens | 8 | ALA4823307 | single protein format | Scientific Literature | |
2. | ALA4825197 | Binding | Inhibition of human ALDH1A1 assessed as NADH formation using propionaldehyde as substrate at 10 uM by spectrophotometry | Homo sapiens | 53 | ALA4823307 | single protein format | Scientific Literature | |
3. | ALA4825198 | Binding | Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometry | Homo sapiens | 7 | ALA4823307 | single protein format | Scientific Literature | |
4. | ALA4825199 | Binding | Inhibition of human ALDH1A3 assessed as NADH formation using propionaldehyde as substrate by spectrophotometry | Homo sapiens | 7 | ALA4823307 | single protein format | Scientific Literature | |
5. | ALA4825200 | Binding | Inhibition of human ALDH2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometry | Homo sapiens | 7 | ALA4823307 | single protein format | Scientific Literature | |
6. | ALA4825201 | Binding | Inhibition of human ALDH3A1 assessed as NADH formation using propionaldehyde as substrate by spectrophotometry | Homo sapiens | 7 | ALA4823307 | single protein format | Scientific Literature | |
7. | ALA4825202 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 0.1 uM incubated for 24 hrs by MTT assay relative to control | Homo sapiens | 6 | ALA4823307 | cell-based format | Scientific Literature | |
8. | ALA4825203 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 1 uM incubated for 24 hrs by MTT assay relative to control | Homo sapiens | 6 | ALA4823307 | cell-based format | Scientific Literature | |
9. | ALA4825204 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 10 uM incubated for 24 hrs by MTT assay relative to control | Homo sapiens | 6 | ALA4823307 | cell-based format | Scientific Literature | |
10. | ALA4825205 | ADME | Cytotoxicity against human HepG2 cells assessed as morphological changes at 0.1 to 10 uM incubated for 24 hrs | Homo sapiens | 5 | ALA4823307 | cell-based format | Scientific Literature | |
11. | ALA4825206 | Functional | Increase in glucose consumption in human HepG2 cells at 10 uM by glucose oxidase assay | Homo sapiens | 6 | ALA4823307 | cell-based format | Scientific Literature | |
12. | ALA4825207 | ADME | Metabolic stability in human liver microsomes assessed as half life at 2 ug/ml measured up to 45 mins by LC-MS/MS analysis | Homo sapiens | 3 | ALA4823307 | microsome format | Scientific Literature | |
13. | ALA4825208 | ADME | Metabolic stability in human liver microsomes assessed as intrinsic clearance at 2 ug/ml measured up to 45 mins by LC-MS/MS analysis | Homo sapiens | 3 | ALA4823307 | microsome format | Scientific Literature | |
14. | ALA4825209 | ADME | Metabolic stability in human liver microsomes assessed as first order elimination rate constant at 2 ug/ml measured up to 45 mins by LC-MS/MS analysis | Homo sapiens | 3 | ALA4823307 | microsome format | Scientific Literature | |
15. | ALA4825210 | ADME | Metabolic stability in human liver microsomes assessed as protein concentration in liver microsomal at 2 ug/ml measured up to 45 mins by LC-MS/MS analysis | Homo sapiens | 3 | ALA4823307 | microsome format | Scientific Literature |