| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4814790 | B | Displacement of [3H]-SCH23390 from dopamine D5 receptor (unknown origin) expressed in HEK-293T cells at 10 uM | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA4814791 | B | Displacement of [3H]-citalopram from SERT (unknown origin) expressed in HEK cells at 10 uM relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA4814792 | B | Displacement of [3H]-alpha-methylhistamine from histamine H3 receptor (unknown origin) expressed in Flp-In-293 cells at 10 uM relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 4. | ALA4814793 | B | Displacement of [3H]-U69593 from kappa opioid receptor (unknown origin) expressed in HEK cells at 10 uM | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 5. | ALA4814794 | B | Displacement of [3H]-DADLE from delta opioid receptor (unknown origin) expressed in HEK cells at 10 uM | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA4814795 | B | Displacement of [3H]-DAMGO from mu opioid receptor (unknown origin) expressed in HEK cells at 10 uM | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 7. | ALA4814796 | B | Displacement of [3H]-SCH23390 from dopamine D5 receptor (unknown origin) expressed in HEK-293T cells assessed as inhibition constant | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA4814797 | B | Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA4814798 | B | Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 10. | ALA4814799 | B | Displacement of [3H]-DPDPE from human delta opioid receptor expressed in CHO-K1 cells by radioligand binding assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 11. | ALA4814800 | F | Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincubated for 20 mins followed by forskolin stimulation and measured after 15 mins by Glo-sensor reagent based assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 12. | ALA4814801 | F | Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincubated for 20 mins followed by forskolin stimulation and measured after 15 mins by Glo-sensor reagent based assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 13. | ALA4814802 | F | Agonist activity at mouse FLAG-tagged delta opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincubated for 20 mins followed by forskolin stimulation and measured after 15 mins by Glo-sensor reagent based assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 14. | ALA4814814 | F | Antinociceptive activity against C57Bl/6N mouse model of thermal-induced nociception at 3 mg/kg, sc measured at 110 mins by tail-flick test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4814815 | F | Antinociceptive activity against C57Bl/6N mouse model of thermal-induced nociception at 60 mg/kg, sc measured at 30 mins by tail-flick test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4814816 | F | Antinociceptive activity against C57Bl/6N mouse model of thermal-induced nociception at 3 mg/kg, sc measured at 110 mins by hot-plate test | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA4814817 | F | Antinociceptive activity against C57Bl/6N mouse model of thermal-induced nociception at 30 mg/kg, sc measured at 60 mins by hot-plate test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4814818 | F | Antinociceptive activity against C57Bl/6N mouse model of thermal-induced nociception at 60 mg/kg, sc measured at 30 mins by hot-plate test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4814821 | F | Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincubated for 20 mins followed by forskolin stimulation and measured after 15 mins by Glo-sensor reagent based assay relative to DAMGO | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 20. | ALA4814823 | F | Agonist activity at mouse FLAG-tagged delta opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincubated for 20 mins followed by forskolin stimulation and measured after 15 mins by Glo-sensor reagent based assay relative to Leu-Enk | Mus musculus | 4 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!