# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4842515 | F | Anti-necroptotic activity in human HT-29 cells assessed as inhibition of hTNFalpha/Z-VAD-fmk (TSZ)-induced necroptosis by measuring increase in cell viability measured after 8 to 10 hrs by celltiter-glo luminescent cell viability assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
2. | ALA4842516 | A | Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 8 to 10 hrs by celltiter-glo luminescent cell viability assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
3. | ALA4842517 | F | Anti-necroptotic activity in human HT-29 cells assessed as inhibition of Z-VAD-fmk (TSZ)-induced necroptosis by measuring increase in cell viability measured after 8 to 10 hrs by celltiter-glo luminescent cell viability assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA4842518 | B | Inhibition of RIPK1 phosphorylation in Z-VAD-fmk (TSZ)-induced human HT-29 cells at 1 uM measured up to 4 hrs by immunoblotting analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
5. | ALA4842519 | B | Inhibition of RIPK3 phosphorylation in Z-VAD-fmk (TSZ)-induced human HT-29 cells at 1 uM measured up to 4 hrs by immunoblotting analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
6. | ALA4842520 | B | Inhibition of MLKL phosphorylation in Z-VAD-fmk (TSZ)-induced human HT-29 cells at 1 uM measured up to 4 hrs by immunoblotting analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
7. | ALA4842521 | B | Inhibition of RIPK1 phosphorylation in Z-VAD-fmk (TSZ)-induced human HT-29 cells measured at 4 hrs by immunoblotting analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
8. | ALA4842522 | B | Inhibition of RIPK3 phosphorylation in Z-VAD-fmk (TSZ)-induced human HT-29 cells measured at 4 hrs by immunoblotting analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
9. | ALA4842523 | B | Inhibition of MLKL phosphorylation in Z-VAD-fmk (TSZ)-induced human HT-29 cells measured at 4 hrs by immunoblotting analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
10. | ALA4842524 | B | Inhibition of RIPK1 in Z-VAD-fmk (TSZ)-induced human HT-29 cells assessed as reduction in RIPK1-RIPK3 necrosome formation at 1 uM measured after 6 hrs by Western blot analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
11. | ALA4842525 | B | Inhibition of RIPK3 in Z-VAD-fmk (TSZ)-induced human HT-29 cells assessed as reduction in RIPK1-RIPK3 necrosome formation at 1 uM measured after 6 hrs by Western blot analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature |