# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4832686 | B | Reversible inhibition of Trypanosoma brucei rhodesain assessed as reversibility by measuring residual enzymatic activity using Cbz-Phe-Arg-AMC as substrate after 1 hr by fluorometry based dialysis experiment relative to control | Trypanosoma brucei | 3 | single protein format | Scientific Literature | ||
2. | ALA4832689 | F | Antiprotozoal activity against Trypanosoma brucei brucei TC211 assessed as luminescence incubated for 24 to 48 hrs by ATPlite assay | Trypanosoma brucei brucei | 4 | organism-based format | Scientific Literature | ||
3. | ALA4832690 | F | Cytotoxicity against mouse J774.1 cells by Alamar blue assay | Mus musculus | 11 | cell-based format | Scientific Literature | ||
4. | ALA4832691 | F | Cytotoxicity against human HeLa cells by Alamar blue assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
5. | ALA4832692 | B | Inhibition of trypsin-like activity of human 20S proteasome at 11 uM using boc-Leu-Arg-Arg-AMC as fluorogenic substrate by microplate reader relative to control | Homo sapiens | 10 | single protein format | Scientific Literature | ||
6. | ALA4832693 | B | Inhibition of caspase-like activity of human 20S proteasome at 11 uM using Cbz-Leu-Leu-Glu-AMC as fluorogenic substrate by microplate reader relative to control | Homo sapiens | 10 | assay format | Scientific Literature | ||
7. | ALA4832694 | B | Inhibition of alpha-chymotrypsin-like activity of human 20S proteasome at 11 uM using Succ-Leu-Leu-Val-Tyr-AMC as fluorogenic substrate by microplate reader relative to control | Homo sapiens | 10 | assay format | Scientific Literature | ||
8. | ALA4832695 | B | Inhibition of Dengue virus NS2B-NS3 protease assessed as fluorescent emission using boc-Gly-Arg-Arg-AMC at 11 uM by microplate reader relative to control | Dengue virus | 10 | assay format | Scientific Literature |