# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4822329 | F | Antiviral activity against RSV infected in human A549 cells assessed as reduction in viral titer at 10 uM incubated for 15 hrs by immunostaining analysis | Respiratory syncytial virus | 21 | organism-based format | Scientific Literature | ||
2. | ALA4822330 | A | Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 15 hrs by LDH assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
3. | ALA4822331 | F | Antiinflammatory activity against in human A549 cells transfected with PRDIII-I-Luc and IRF-3-Luc assessed as reduction in RSV-induced IRF3 activation at 10 uM incubated for 15 hrs by luciferase reporter gene assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
4. | ALA4822332 | F | Antiinflammatory activity against in human A549 cells transfected with NF-kappaB-Luc assessed as reduction in RSV-induced NF-kappaB activation at 10 uM incubated for 15 hrs by luciferase reporter gene assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
5. | ALA4822333 | F | Antiinflammatory activity against in human A549 cells assessed as reduction in RSV-induced IRF3 mRNA expression at 10 uM incubated for 4 hrs by qRT-PCR analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
6. | ALA4822334 | F | Antiinflammatory activity against in human A549 cells assessed as reduction in RSV-induced NF-kappaB mRNA expression at 10 uM incubated for 4 hrs by qRT-PCR analysis | Homo sapiens | 7 | cell-based format | Scientific Literature |