# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4823699 | Binding | Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as substrate incubated for 30 mins in presence of ATP by ELISA | Homo sapiens | 32 | ALA4823251 | single protein format | Scientific Literature | |
2. | ALA4823700 | Binding | Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity assay | Homo sapiens | 32 | ALA4823251 | cell-based format | Scientific Literature | |
3. | ALA4823701 | Binding | Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 mins in presence of ATP at Km concentration by luminescence assay | Homo sapiens | 29 | ALA4823251 | assay format | Scientific Literature | |
4. | ALA4823703 | Physicochemical | Kinetic solubility of the compound in pH 7.4 PBS buffer incubated for 2 hrs using orbital shaker by LC-UV mass spectrometry | 31 | ALA4823251 | small-molecule physicochemical format | Scientific Literature |