# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4831101 | Binding | Displacement of [3H]LSD from human 5HT6 receptor expressed in CHO-K1 membrane incubated for 60 mins by solid scintillation counting analysis | Homo sapiens | 54 | ALA4828761 | cell membrane format | Scientific Literature | |
2. | ALA4831102 | Functional | Antagonist activity at human 5HT6 receptor expressed in human 1321N1 cells assessed as inhibition of serotonin-induced cAMP accumulation incubated for 30 mins by TR-FRET assay | Homo sapiens | 14 | ALA4828761 | cell-based format | Scientific Literature | |
3. | ALA4831103 | Binding | Inhibition of equine serum BuChE using BTC as substrate preincubated with enzyme for 5 mins followed by substrate addition for 5 mins by Ellman's method | Equus caballus | 52 | ALA4828761 | cell-free format | Scientific Literature | |
4. | ALA4831104 | Binding | Inhibition of BuChE in human plasma using BTC as substrate preincubated with enzyme for 5 mins followed by substrate addition for 5 mins by Ellman's method | Homo sapiens | 14 | ALA4828761 | cell-free format | Scientific Literature | |
5. | ALA4831105 | Binding | Inhibition of electric eel AchE using ATC as substrate at 10 uM preincubated with enzyme for 5 mins followed by substrate addition for 5 mins by Ellman's method relative to control | Electrophorus electricus | 51 | ALA4828761 | single protein format | Scientific Literature | |
6. | ALA4831106 | Binding | Inhibition of amyloid beta (1 to 42) (unknown origin) self aggregation at 10 uM incubated for 24 to 48 hrs by Thioflavin-T based fluorometric assay | Homo sapiens | 53 | ALA4828761 | single protein format | Scientific Literature | |
7. | ALA4831136 | Binding | Inhibition of equine serum BuChE using BTC as substrate at 10 uM preincubated with enzyme for 5 mins followed by substrate addition for 5 mins by Ellman's method relative to control | Equus caballus | 55 | ALA4828761 | cell-free format | Scientific Literature | |
8. | ALA4831137 | Binding | Inhibition of BuChE in human plasma using BTC as substrate at 10 uM preincubated with enzyme for 5 mins followed by substrate addition for 5 mins by Ellman's method relative to control | Homo sapiens | 57 | ALA4828761 | cell-free format | Scientific Literature |