#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4844258	Binding	Inhibition of human recombinant BACE-1 expressed in Escherichia coli at 10 uM using panvera peptide as a substrate incubated for 1 hr by fluorescence analysis relative to control	Homo sapiens	5	ALA4842362	assay format	Scientific Literature
2.	ALA4844259	Binding	Inhibition of human recombinant AChE using acetylthiocholine iodide as a substrate preincubated for 20 mins followed by substrate addition by spectrophotometric analysis	Homo sapiens	13	ALA4842362	single protein format	Scientific Literature
3.	ALA4844260	Binding	Inhibition of human serum BChE using butyrylthiocholine iodide as a substrate preincubated for 20 mins followed by substrate addition by spectrophotometric analysis	Homo sapiens	13	ALA4842362	cell-free format	Scientific Literature
4.	ALA4844261	Binding	Potency index, ratio of rhein-huprine hybrid IC50 to test compound IC50 for inhibition of human recombinant AChE using acetylthiocholine iodide as a substrate preincubated for 20 mins followed by substrate addition by spectrophotometric analysis	Homo sapiens	7	ALA4842362	single protein format	Scientific Literature
5.	ALA4844262	Binding	Potency index, ratio of donepezil IC50 to test compound IC50 for inhibition of human recombinant AChE using acetylthiocholine iodide as a substrate preincubated for 20 mins followed by substrate addition by spectrophotometric analysis	Homo sapiens	7	ALA4842362	single protein format	Scientific Literature
6.	ALA4844263	Binding	Potency index, ratio of rhein-huprine hybrid IC50 to test compound IC50 for inhibition of human serum BChE using butyrylthiocholine iodide as a substrate preincubated for 20 mins followed by substrate addition by spectrophotometric analysis	Homo sapiens	7	ALA4842362	cell-free format	Scientific Literature
7.	ALA4844264	Binding	Potency index, ratio of huprine-Y IC50 to test compound IC50 for inhibition of human serum BChE using butyrylthiocholine iodide as a substrate preincubated for 20 mins followed by substrate addition by spectrophotometric analysis	Homo sapiens	7	ALA4842362	cell-free format	Scientific Literature
8.	ALA4844265	Binding	Potency index, ratio of donepezil IC50 to test compound IC50 for inhibition of human serum BChE using butyrylthiocholine iodide as a substrate preincubated for 20 mins followed by substrate addition by spectrophotometric analysis	Homo sapiens	7	ALA4842362	cell-free format	Scientific Literature
9.	ALA4844266	Binding	Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation in Escherichia coli BL21 (DE3) at 10 uM incubated overnight by thioflavin S based fluorescence analysis relative to control	Homo sapiens	13	ALA4842362	single protein format	Scientific Literature
10.	ALA4844267	Binding	Inhibition of tau aggregation (unknown origin) in Escherichia coli BL21 (DE3) at 10 uM incubated overnight by thioflavin S based fluorescence analysis relative to control	Homo sapiens	13	ALA4842362	single protein format	Scientific Literature
11.	ALA4844274	Functional	Antioxidant activity assessed as free radical scavenging activity at 500 uM incubated for 30 mins under dark condition by DPPH assay		5	ALA4842362	assay format	Scientific Literature
12.	ALA4844278	ADME	Neurotoxicity in mouse HT-22 cells assessed as decrease in cell viability at up to 25 uM by MTT assay	Mus musculus	6	ALA4842362	cell-based format	Scientific Literature
13.	ALA4844280	Toxicity	Acute toxicity in zebra fish embryos assessed as lowest observed adverse effect concentration measured every 24 hrs for 72 hrs	Danio rerio	8	ALA4842362	assay format	Scientific Literature
14.	ALA4844281	Toxicity	Acute toxicity in zebra fish embryos assessed as lethality measured every 24 hrs for 72 hrs	Danio rerio	8	ALA4842362	assay format	Scientific Literature
15.	ALA4844282	Toxicity	Acute toxicity in zebra fish embryos assessed as lethality at 12.5 to 100 uM measured every 24 hrs for 72 hrs relative to control	Danio rerio	1	ALA4842362	assay format	Scientific Literature
16.	ALA4844283	ADME	Permeability of the compound in PBS/EtOH by PAMPA-BBB assay		8	ALA4842362	assay format	Scientific Literature
17.	ALA4844284	Physicochemical	Kinetic solubility of the compound in DMSO/PBS buffer measured after 2 hrs by nephalometric analysis		8	ALA4842362	small-molecule physicochemical format	Scientific Literature