# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4837883 | B | Inhibition of FAM-Bim peptide binding to human Hsp70 NBD (1 to 383) measured after 30 mins by fluorescence polarization assay | Homo sapiens | 19 | ALA4837197 | assay format | Scientific Literature | |
2. | ALA4837884 | B | Inhibition of FAM-Bim peptide binding to human Bcl-2 (2 to 206) measured after 30 mins by fluorescence polarization assay | Homo sapiens | 19 | ALA4837197 | single protein format | Scientific Literature | |
3. | ALA4837885 | B | Binding affinity to human Hsp70 NBD (1 to 383) assessed as dissociation constant measured by isothermal titration calorimetry assay | Homo sapiens | 2 | ALA4837197 | assay format | Scientific Literature | |
4. | ALA4837886 | B | Inhibition of BimBH3-stimulated human HSP70 ATPase activity | Homo sapiens | 3 | ALA4837197 | assay format | Scientific Literature | |
5. | ALA4837887 | B | Competitive binding affinity to HSP70 in human BV-173 cell lysate by pull-down/Western blot analysis | Homo sapiens | 1 | ALA4837197 | subcellular format | Scientific Literature | |
6. | ALA4837888 | F | Induction of apoptosis in human BV-173 cells by AnnexinV-FITC/PI staining based flow cytometric analysis | Homo sapiens | 3 | ALA4837197 | cell-based format | Scientific Literature | |
7. | ALA4837889 | F | Induction of apoptosis in human KCL-22 cells by AnnexinV-FITC/PI staining based flow cytometric analysis | Homo sapiens | 3 | ALA4837197 | cell-based format | Scientific Literature | |
8. | ALA4837890 | A | Induction of apoptosis in human HEK293 cells by AnnexinV-FITC/PI staining based flow cytometric analysis | Homo sapiens | 3 | ALA4837197 | cell-based format | Scientific Literature | |
9. | ALA4837891 | A | Induction of apoptosis in mouse BaF3 cells by AnnexinV-FITC/PI staining based flow cytometric analysis | Mus musculus | 3 | ALA4837197 | cell-based format | Scientific Literature | |
10. | ALA4837892 | B | Inhibition of Hsp70/Bim protein protein interaction in human BV-173 cells assessed as decrease in Akt phosphorylation at 3 uM by Western blot analysis | Homo sapiens | 1 | ALA4837197 | cell-based format | Scientific Literature | |
11. | ALA4837893 | B | Inhibition of Hsp70/Bim protein protein interaction in human BV-173 cells assessed as decrease in Raf-1 phosphorylation at 3 uM by Western blot analysis | Homo sapiens | 1 | ALA4837197 | cell-based format | Scientific Literature | |
12. | ALA4837894 | B | Inhibition of Hsp70/Bim protein protein interaction in human KCL-22 cells assessed as decrease in Akt phosphorylation at 3 uM by Western blot analysis | Homo sapiens | 1 | ALA4837197 | cell-based format | Scientific Literature | |
13. | ALA4837895 | B | Inhibition of Hsp70/Bim protein protein interaction in human KCL-22 cells assessed as decrease in Raf-1 phosphorylation at 3 uM by Western blot analysis | Homo sapiens | 1 | ALA4837197 | cell-based format | Scientific Literature | |
14. | ALA4837896 | B | Inhibition of Hsp70/Bim protein protein interaction in human BV-173 cells assessed as decrease in Akt expression at 3 uM by Western blot analysis | Homo sapiens | 1 | ALA4837197 | cell-based format | Scientific Literature | |
15. | ALA4837897 | B | Inhibition of Hsp70/Bim protein protein interaction in human BV-173 cells assessed as decrease in Raf-1 expression at 3 uM by Western blot analysis | Homo sapiens | 1 | ALA4837197 | cell-based format | Scientific Literature | |
16. | ALA4837898 | B | Inhibition of Hsp70/Bim protein protein interaction in human KCL-22 cells assessed as decrease in Akt expression at 3 uM by Western blot analysis | Homo sapiens | 1 | ALA4837197 | cell-based format | Scientific Literature | |
17. | ALA4837899 | B | Inhibition of Hsp70/Bim protein protein interaction in human KCL-22 cells assessed as decrease in Raf-1 expression at 3 uM by Western blot analysis | Homo sapiens | 1 | ALA4837197 | cell-based format | Scientific Literature | |
18. | ALA4837900 | B | Competitive binding affinity to Mortalin in human BV-173 cell lysate up to 10 uM by pull-down/Western blot analysis | Homo sapiens | 1 | ALA4837197 | subcellular format | Scientific Literature | |
19. | ALA4837901 | B | Competitive binding affinity to Hsc70 in human BV-173 cell lysate up to 10 uM by pull-down/Western blot analysis | Homo sapiens | 1 | ALA4837197 | subcellular format | Scientific Literature | |
20. | ALA4837902 | B | Inhibition of Hsp70/Bim protein protein interaction in human BV-173 cell lysate at 1 to 5 uM by co-IP/Western blot analysis | Homo sapiens | 2 | ALA4837197 | subcellular format | Scientific Literature |