# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4810079 | B | Inhibition of human recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 22 to 24 hrs by RapidFire Mass spectroscopy | Homo sapiens | 27 | single protein format | Scientific Literature | ||
2. | ALA4810080 | B | Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 22 to 24 hrs by RapidFire Mass spectroscopy | Mus musculus | 27 | single protein format | Scientific Literature | ||
3. | ALA4810081 | B | Inhibition of human NNMT expressed in HEK293 cells assessed as reduction in 1-methyl-nicotinamide formation measured after 24 hrs by RapidFire Mass spectroscopy | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
4. | ALA4810082 | A | Cytotoxicity against human HEK293 cells overexpressing human NNMT assessed as reduction in ATP level measured after 24 hrs by CellTiter-glo luminescence assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
5. | ALA4810083 | B | Ratio of IC50 for inhibition of human NNMT expressed in HEK293 cells to IC50 for inhibition of human recombinant NNMT | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA4810086 | B | Inhibition of human recombinant INMT using 9H-Pyrido[3,4-b]indole and S-(5'-Adenosyl)-L-methionine chloride dihydrochloride as substrate incubated for 2.5 hrs by MTase-Glo assay | Homo sapiens | 2 | single protein format | Scientific Literature |