| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4808842 | B | Inhibition of recombinant full length GST-tagged PDE5A1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using TAMRA-cGMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 75 | ALA4808175 | cell-based format | Scientific Literature | |
| 2. | ALA4808843 | B | Inhibition of recombinant 6His-tagged PDE5A1 catalytic domain (unknown origin) expressed in Escherichia coli using TAMRA-cGMP or FAM-cAMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 2 | ALA4808175 | assay format | Scientific Literature | |
| 3. | ALA4808844 | B | Inhibition of recombinant full length GST-tagged PDE1A (unknown origin) expressed in baculovirus infected Sf9 insect cells using FAM-cAMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 4. | ALA4808845 | B | Inhibition of recombinant full length GST-tagged PDE1A (unknown origin) expressed in baculovirus infected Sf9 insect cells using TAMRA-cGMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 5. | ALA4808846 | B | Inhibition of recombinant full length GST-tagged PDE2A (unknown origin) expressed in baculovirus infected Sf9 insect cells using FAM-cAMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 6. | ALA4808847 | B | Inhibition of recombinant full length GST-tagged PDE2A (unknown origin) expressed in baculovirus infected Sf9 insect cells using TAMRA-cGMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 7. | ALA4808848 | B | Inhibition of recombinant GST-tagged PDE3A (669 to end residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using FAM-cAMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 8. | ALA4808849 | B | Inhibition of recombinant GST-tagged PDE3A (669 to end residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using TAMRA-cGMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 9. | ALA4808850 | B | Inhibition of recombinant full length GST-tagged PDE4B2 (unknown origin) expressed in baculovirus infected Sf9 insect cells using FAM-cAMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 10. | ALA4808851 | B | Inhibition of recombinant full length GST-tagged PDE6C (unknown origin) expressed in baculovirus infected Sf9 insect cells using TAMRA-cGMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 11. | ALA4808852 | B | Inhibition of recombinant GST-tagged PDE7A (122 to end residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using FAM-cAMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 12. | ALA4808853 | B | Inhibition of recombinant GST-tagged full length PDE8A1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using FAM-cAMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 13. | ALA4808854 | B | Inhibition of recombinant GST-tagged full length PDE9A2 (unknown origin) expressed in baculovirus infected Sf9 insect cells using FAM-cAMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 14. | ALA4808855 | B | Inhibition of recombinant GST-tagged full length PDE10A2 (unknown origin) expressed in baculovirus infected Sf9 insect cells using FAM-cAMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 15. | ALA4808856 | B | Inhibition of recombinant GST-tagged full length PDE10A2 (unknown origin) expressed in baculovirus infected Sf9 insect cells using TAMRA-cGMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 16. | ALA4808857 | B | Inhibition of recombinant GST-tagged full length PDE11A4 (unknown origin) expressed in baculovirus infected Sf9 insect cells using FAM-cAMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 17. | ALA4808858 | B | Inhibition of recombinant GST-tagged full length PDE11A4 (unknown origin) expressed in baculovirus infected Sf9 insect cells using TAMRA-cGMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 18. | ALA4808859 | B | Selectivity ratio of IC50 for recombinant full length GST-tagged PDE6C (unknown origin) expressed in baculovirus infected Sf9 insect cells to IC50 for recombinant full length GST-tagged PDE5A1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using TAMRA-cGMP as substrate incubated for 1.5 hrs by IMAP-FP assay using TAMRA-cGMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 19. | ALA4808860 | B | Selectivity ratio of IC50 for recombinant GST-tagged full length PDE11A4 (unknown origin) expressed in baculovirus infected Sf9 insect cells to IC50 for recombinant full length GST-tagged PDE5A1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using TAMRA-cGMP as substrate incubated for 1.5 hrs by IMAP-FP assay using TAMRA-cGMP as substrate incubated for 1.5 hrs by IMAP-FP assay | Homo sapiens | 5 | ALA4808175 | cell-based format | Scientific Literature | |
| 20. | ALA4808862 | A | Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated with enzyme for 5 mins followed by incubation with substrate for 5 mins by colorimetric analysis | Ovis aries | 7 | ALA4808175 | single protein format | Scientific Literature |
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