# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4821271 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as increase in NQO1 activity at 0.4 uM | Mus musculus | 4 | cell-based format | Scientific Literature | ||
2. | ALA4821272 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as increase in NQO1 activity at 0.8 uM | Mus musculus | 4 | cell-based format | Scientific Literature | ||
3. | ALA4821273 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as increase in NQO1 activity at 1.6 uM | Mus musculus | 4 | cell-based format | Scientific Literature | ||
4. | ALA4821274 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as increase in NQO1 activity at 3.125 uM | Mus musculus | 4 | cell-based format | Scientific Literature | ||
5. | ALA4821275 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as increase in NQO1 activity at 6.25 uM | Mus musculus | 4 | cell-based format | Scientific Literature | ||
6. | ALA4821276 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as increase in NQO1 activity at 12.5 uM | Mus musculus | 4 | cell-based format | Scientific Literature | ||
7. | ALA4821277 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as increase in NQO1 activity at 25 uM | Mus musculus | 3 | cell-based format | Scientific Literature | ||
8. | ALA4821278 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as increase in NQO1 activity at 50 uM | Mus musculus | 3 | cell-based format | Scientific Literature | ||
9. | ALA4821287 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as concentration required to double induction to increase in NQO1 activity | Mus musculus | 2 | cell-based format | Scientific Literature | ||
10. | ALA4821288 | F | Antioxidant activity assessed as DPPH radical scavenging activity | 16 | assay format | Scientific Literature | |||
11. | ALA4821289 | T | Toxicity in albino mouse assessed as lethality | Mus musculus | 1 | assay format | Scientific Literature | ||
12. | ALA4821290 | F | Radioprotective activity in albino mouse assessed as RBC level at 50 mg/kg, ip administered for 5 days and on day 5 irradiated with gamma radiation and measured after 3 days (Rvb = 5.89 +/- 0.27 10^6/UL) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA4821291 | F | Radioprotective activity in albino mouse assessed as WBC level at 50 mg/kg, ip administered for 5 days and on day 5 irradiated with gamma radiation and measured after 3 days (Rvb = 0.40 +/- 0.03 10^3/UL) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
14. | ALA4821292 | F | Radioprotective activity in albino mouse assessed as HGB level at 50 mg/kg, ip administered for 5 days and on day 5 irradiated with gamma radiation and measured after 3 days (Rvb = 7.98 +/- 0.24 g/dL) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
15. | ALA4821293 | F | Radioprotective activity in albino mouse assessed as HCT level at 50 mg/kg, ip administered for 5 days and on day 5 irradiated with gamma radiation and measured after 3 days (Rvb = 23.05 +/- 0.98 %) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
16. | ALA4821294 | F | Radioprotective activity in albino mouse assessed as PLT level at 50 mg/kg, ip administered for 5 days and on day 5 irradiated with gamma radiation and measured after 3 days (Rvb = 500.3 +/- 49.73 10^3/UL) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
17. | ALA4821295 | F | Radioprotective activity in albino mouse assessed as Nrf2 level at 50 mg/kg, ip administered for 5 days and on day 5 irradiated with gamma radiation and measured after 3 days (Rvb = 23 %) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
18. | ALA4821296 | F | Radioprotective activity in albino mouse assessed as NQO1 level at 50 mg/kg, ip administered for 5 days and on day 5 irradiated with gamma radiation and measured after 3 days (Rvb = 192 %) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
19. | ALA4821297 | F | Radioprotective activity in albino mouse assessed as ROS level at 50 mg/kg, ip administered for 5 days and on day 5 irradiated with gamma radiation and measured after 3 days (Rvb = 39 %) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
20. | ALA4821298 | F | Radioprotective activity in albino mouse assessed as MDA level at 50 mg/kg, ip administered for 5 days and on day 5 irradiated with gamma radiation and measured after 3 days (Rvb = 86 %) | Mus musculus | 1 | organism-based format | Scientific Literature |