# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4836402 | B | Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins followed by substate addition and measured after 30 mins by LC-MS/MS analysis | Homo sapiens | 17 | mitochondrion format | Scientific Literature | ||
2. | ALA4836403 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance incubated for 30 mins in presence of NADPH measured per mg protein | Homo sapiens | 17 | microsome format | Scientific Literature | ||
3. | ALA4836404 | A | Metabolic stability in rat liver microsomes assessed as intrinsic clearance incubated for 30 mins in presence of NADPH measured per mg protein | Rattus norvegicus | 17 | microsome format | Scientific Literature | ||
4. | ALA4836405 | P | Glutathione reactivity assessed as dansylatedGSH-compound conjugate formation in presence of human liver microsomes by fluorescence detector based HPLC analysis | 17 | microsome format | Scientific Literature |