# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4811142 | Binding | Inhibition of AChE in human erythrocytes using acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured after 30 mins by Ellman's method | Homo sapiens | 16 | ALA4808254 | cell-based format | Scientific Literature | |
2. | ALA4811144 | Binding | Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured after 30 mins by Ellman's method | Equus caballus | 21 | ALA4808254 | cell-free format | Scientific Literature | |
3. | ALA4811146 | Functional | Antioxidant activity assessed as DPPH radical scavenging activity at 20 uM measured after 25 mins by microplate reader based assay relative to control | 14 | ALA4808254 | assay format | Scientific Literature | ||
4. | ALA4811147 | Functional | Antioxidant activity assessed as DPPH radical scavenging activity measured after 25 mins by microplate reader based assay | 16 | ALA4808254 | assay format | Scientific Literature | ||
5. | ALA4811148 | Binding | Mixed inhibition of human erythrocyte AChE using different concentration of acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins by Lineweaver-Burk plot analysis | Homo sapiens | 2 | ALA4808254 | tissue-based format | Scientific Literature | |
6. | ALA4811149 | Binding | Mixed inhibition of equine serum BChE using different concentration of butyrylthiocholine iodide as substrate preincubated with enzyme for 30 mins by Lineweaver-Burk plot analysis | Equus caballus | 2 | ALA4808254 | cell-free format | Scientific Literature | |
7. | ALA4811150 | Binding | Displacement of propidium iodide from the PAS site of human AChE at 5 uM preincubated with enzyme for 6 hrs followed by incubation with propidium iodide and measured after 20 mins by fluorescence analysis | Homo sapiens | 4 | ALA4808254 | single protein format | Scientific Literature | |
8. | ALA4811151 | Binding | Displacement of propidium iodide from the PAS site of human AChE at 10 uM preincubated with enzyme for 6 hrs followed by incubation with propidium iodide and measured after 20 mins by fluorescence analysis | Homo sapiens | 4 | ALA4808254 | single protein format | Scientific Literature | |
9. | ALA4811152 | Binding | Displacement of propidium iodide from the PAS site of human AChE at 20 uM preincubated with enzyme for 6 hrs followed by incubation with propidium iodide and measured after 20 mins by fluorescence analysis | Homo sapiens | 4 | ALA4808254 | single protein format | Scientific Literature | |
10. | ALA4811153 | Binding | Displacement of propidium iodide from the PAS site of human AChE at 50 uM preincubated with enzyme for 6 hrs followed by incubation with propidium iodide and measured after 20 mins by fluorescence analysis | Homo sapiens | 4 | ALA4808254 | single protein format | Scientific Literature | |
11. | ALA4811157 | ADME | Permeability of the compound in PBS buffer at pH 7.4 at 500 uM incubated for 18 hrs by PAMPA-BBB assay | 6 | ALA4808254 | assay format | Scientific Literature |