# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4835450 | Binding | Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus infected Sf21 insect cells using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by HTRF assay | Homo sapiens | 41 | ALA4834420 | cell-based format | Scientific Literature | |
2. | ALA4835451 | Binding | Selectivity ratio of IC50 for N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus infected Sf21 insect cells to IC50 for N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus infected Sf21 insect cells | Homo sapiens | 41 | ALA4834420 | cell-based format | Scientific Literature | |
3. | ALA4835452 | Binding | Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated for 20 mins followed by anti-IgM antibody stimulation and measured after 30 mins by alphascreen assay | Homo sapiens | 38 | ALA4834420 | cell-based format | Scientific Literature | |
4. | ALA4835453 | Binding | Inhibition of adenosine transporter in human HeLa cells assessed as reduction in [3H]adenosine uptake preincubated for 30 mins followed by [3H]adenosine addition and measured after 60 mins | Homo sapiens | 36 | ALA4834420 | cell-based format | Scientific Literature |