# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4819609 | Binding | Inhibition of recombinant NAMPT (unknown origin) using nicotinamide and pyrophosphate as substrate incubated for 60 mins and measured for 30 mins at 5 mins interval by colorimetric assay | Homo sapiens | 8 | ALA4818995 | single protein format | Scientific Literature | |
2. | ALA4819610 | Binding | Inhibition of N-terminal GST-tagged human recombinant EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression system by Z'-LYTE kinase assay | Homo sapiens | 8 | ALA4818995 | assay format | Scientific Literature | |
3. | ALA4819611 | Binding | Inhibition of N-terminal GST-tagged human recombinant EGFR T790M mutant (668 to 1210 residues) expressed in baculovirus expression system by Z'-LYTE kinase assay | Homo sapiens | 8 | ALA4818995 | assay format | Scientific Literature | |
4. | ALA4819612 | Binding | Inhibition of N-terminal GST-tagged human recombinant EGFR L861Q mutant (668 to 1210 residues) expressed in baculovirus expression system by Z'-LYTE kinase assay | Homo sapiens | 8 | ALA4818995 | assay format | Scientific Literature | |
5. | ALA4819613 | Binding | Inhibition of N-terminal GST-tagged human recombinant EGFR L858R mutant (668 to 1210 residues) expressed in baculovirus expression system by Z'-LYTE kinase assay | Homo sapiens | 8 | ALA4818995 | assay format | Scientific Literature | |
6. | ALA4819614 | Functional | Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth after 72 hrs by CCK8 assay | Homo sapiens | 7 | ALA4818995 | cell-based format | Scientific Literature | |
7. | ALA4819615 | Functional | Antiproliferative activity against human MCF-7 cells assessed as inhibition of cell growth after 72 hrs by CCK8 assay | Homo sapiens | 7 | ALA4818995 | cell-based format | Scientific Literature | |
8. | ALA4819616 | Functional | Antiproliferative activity against human K562 cells assessed as inhibition of cell growth after 72 hrs by CCK8 assay | Homo sapiens | 7 | ALA4818995 | cell-based format | Scientific Literature |