# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4820881 | B | Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incubated for 30 mins by fluorescence-based FLIPR membrane potential blue assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
2. | ALA4820882 | B | Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response incubated for 30 mins by fluorescence-based FLIPR membrane potential blue assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
3. | ALA4820885 | B | Displacement of [3H]strychnine from human glycine receptor subunit alpha-1 expressed in HEK293 cell membranes preincubated for 30 mins followed by [3H]strychnine addition and measured after 30 mins by liquid scintillation counting method | Homo sapiens | 5 | cell membrane format | Scientific Literature | ||
4. | ALA4820886 | B | Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the onset of compound application by patch-clamp assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
5. | ALA4820887 | B | Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the later state of compound application by patch-clamp assay | Homo sapiens | 5 | single protein format | Scientific Literature |