# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4825211 | Functional | Antiviral activity against SARS-CoV-2 isolate USA-WA1/2020 infected in Vero E6 cells assessed as reduction in virus induced cytopathic effect | Severe acute respiratory syndrome coronavirus 2 | 7 | ALA4823308 | organism-based format | Scientific Literature | |
2. | ALA4825212 | Binding | Inhibition of recombinant SARS-CoV-2 main protease using Dabcyl-KTSAVLQ-SGFRKM-E(Edans-NH2) as substrate preincubated for 15 mins followed by substrate addition by FRET based assay | Severe acute respiratory syndrome coronavirus 2 | 21 | ALA4823308 | assay format | Scientific Literature | |
3. | ALA4825213 | ADME | Permeability of compound in PBS at pH 7.4 after 18 hrs by PAMPA | 14 | ALA4823308 | assay format | Scientific Literature | ||
4. | ALA4825215 | Functional | Antiviral activity against SARS-CoV-2 infected in 16HBE14o- cells assessed as inhibition of viral replication after 1 day by Nano-Glo luciferase assay | Severe acute respiratory syndrome coronavirus 2 | 13 | ALA4823308 | organism-based format | Scientific Literature | |
5. | ALA4825220 | ADME | Cytotoxicity against African green monkey Vero E6 cells after 72 hrs by MTT assay | Chlorocebus sabaeus | 13 | ALA4823308 | cell-based format | Scientific Literature | |
6. | ALA4825221 | ADME | Cytotoxicity against human 16HBE14o- after 72 hrs by MTT assay | Homo sapiens | 13 | ALA4823308 | cell-based format | Scientific Literature |