| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4835968 | B | Positive allosteric modulation of C57BL/6 mouse NMDA receptor assessed as fold change in compound potentiated NMDA-induced current relative to NMDA current alone at 30 uM measured after 15 to 30 mins by patch-clamp method | Mus musculus | 61 | ALA4834434 | tissue-based format | Scientific Literature | |
| 2. | ALA4835982 | B | Positive allosteric modulation of C57BL/6 mouse NMDA receptor assessed as potentiation of NMDA-induced current in presence of saturating glutamate by patch-clamp method | Mus musculus | 6 | ALA4834434 | tissue-based format | Scientific Literature | |
| 3. | ALA4835983 | B | Positive allosteric modulation of C57BL/6 mouse NMDA receptor assessed as fold change in compound potentiated NMDA-induced current relative to NMDA current alone in presence of saturating glutamate by patch-clamp method | Mus musculus | 6 | ALA4834434 | tissue-based format | Scientific Literature | |
| 4. | ALA4835984 | P | Brain to blood partition coefficient of the compound | 61 | ALA4834434 | tissue-based format | Scientific Literature | ||
| 5. | ALA4835987 | F | Antidepressant activity in ICR mouse assessed as decrease in immobility time at 30 mg/kg, ip measured after 26 mins by forced swim test | Mus musculus | 5 | ALA4834434 | organism-based format | Scientific Literature | |
| 6. | ALA4835988 | F | Antidepressant activity in ICR mouse assessed as decrease in immobility time at 3 to 10 mg/kg, ip measured after 26 mins by forced swim test | Mus musculus | 4 | ALA4834434 | organism-based format | Scientific Literature | |
| 7. | ALA4835989 | A | Effect on locomotor activity in ICR mouse assessed as hyperlocomotion at 10 mg/kg, ip measured after 90 mins | Mus musculus | 5 | ALA4834434 | organism-based format | Scientific Literature | |
| 8. | ALA4835990 | A | Effect on locomotor activity in ICR mouse assessed as hypolocomotion at 10 mg/kg, ip measured after 90 mins | Mus musculus | 5 | ALA4834434 | organism-based format | Scientific Literature | |
| 9. | ALA4835991 | F | Antidepressant activity in ICR mouse aassessed as inhibition of apomorphine-induced climbing behaviour at 10 mg/kg, ip administered prior to APO challenge and measured after 30 mins | Mus musculus | 6 | ALA4834434 | organism-based format | Scientific Literature | |
| 10. | ALA4835992 | B | Displacement of [3H]-methylspiperone from human dopamine D2 receptor expressed in CHO cells incubated for 30 mins by liquid scintillation counting analysis | Homo sapiens | 1 | ALA4834434 | cell-based format | Scientific Literature | |
| 11. | ALA4835993 | B | Displacement of [3H]-methylspiperone from human dopamine D3 receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting analysis | Homo sapiens | 1 | ALA4834434 | cell-based format | Scientific Literature | |
| 12. | ALA4835994 | B | Displacement of [3H]-prazosin from rat adrenergic alpha 1 receptor incubated for 60 mins by liquid scintillation counting analysis | Rattus norvegicus | 1 | ALA4834434 | protein format | Scientific Literature | |
| 13. | ALA4835995 | B | Displacement of [3H]-8-OH-DPAT from human 5HT1AR expressed in CHO cells incubated for 30 mins by liquid scintillation counting analysis | Homo sapiens | 1 | ALA4834434 | cell-based format | Scientific Literature | |
| 14. | ALA4835996 | B | Displacement of [3H]-GR125743 from 5HT1BR (unknown origin) expressed in CHO cells | Homo sapiens | 1 | ALA4834434 | cell-based format | Scientific Literature | |
| 15. | ALA4835997 | B | Displacement of [3H]-ketanserin from human 5HT2AR expressed in CHO cells incubated for 30 mins by liquid scintillation counting analysis | Homo sapiens | 1 | ALA4834434 | cell-based format | Scientific Literature | |
| 16. | ALA4835998 | B | Displacement of [3H]-mesulergine from rat cerebral cortex 5HT2CR incubated for 15 mins by liquid scintillation counting analysis | Rattus norvegicus | 1 | ALA4834434 | tissue-based format | Scientific Literature | |
| 17. | ALA4835999 | B | Displacement of [3H]-LSD from human 5HT6 incubated for 30 mins by liquid scintillation counting analysis | Homo sapiens | 1 | ALA4834434 | single protein format | Scientific Literature | |
| 18. | ALA4836000 | B | Displacement of [3H]-WIN35428 from rat striatum DAT | Rattus norvegicus | 1 | ALA4834434 | tissue-based format | Scientific Literature | |
| 19. | ALA4836001 | B | Displacement of [3H]-Nisoxetine from NET (unknown origin) | Homo sapiens | 1 | ALA4834434 | single protein format | Scientific Literature | |
| 20. | ALA4836002 | B | Displacement of [3H]-paroxetine from SERT (unknown origin) | Homo sapiens | 1 | ALA4834434 | single protein format | Scientific Literature |
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