# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4813534 | Binding | Inhibition of mTOR (unknown origin) | Homo sapiens | 5 | ALA4811304 | single protein format | Scientific Literature | |
2. | ALA4813535 | Binding | Inhibition of HDAC6 (unknown origin) | Homo sapiens | 5 | ALA4811304 | single protein format | Scientific Literature | |
3. | ALA4813536 | Binding | Inhibition of mTOR (unknown origin) at 0.5 uM relative to control | Homo sapiens | 28 | ALA4811304 | single protein format | Scientific Literature | |
4. | ALA4813537 | Binding | Inhibition of HDAC6 (unknown origin) at 0.5 uM relative to control | Homo sapiens | 28 | ALA4811304 | single protein format | Scientific Literature | |
5. | ALA4813538 | Functional | Antiproliferative activity against human MDA-MB-231 cells measured after 48 hrs | Homo sapiens | 1 | ALA4811304 | cell-based format | Scientific Literature | |
6. | ALA4813539 | Functional | Antiproliferative activity against human MDA-MB-436 cells measured after 48 hrs | Homo sapiens | 1 | ALA4811304 | cell-based format | Scientific Literature | |
7. | ALA4813540 | Functional | Antiproliferative activity against human MDA-MB-468 cells measured after 48 hrs | Homo sapiens | 1 | ALA4811304 | cell-based format | Scientific Literature | |
8. | ALA4813541 | ADME | Cytotoxicity against human MCF-10A cells assessed as increase in cell viability | Homo sapiens | 1 | ALA4811304 | cell-based format | Scientific Literature | |
9. | ALA4813542 | ADME | Permeability of the compound | 1 | ALA4811304 | assay format | Scientific Literature | ||
10. | ALA4813543 | Physicochemical | Solubility of the compound | 1 | ALA4811304 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4813544 | Binding | Binding affinity to HDAC1 in human MDA-MB-231 cells assessed as increase in thermal stability at 10 uM measured at 6 hrs by CETSA | Homo sapiens | 1 | ALA4811304 | cell-based format | Scientific Literature | |
12. | ALA4813545 | Binding | Binding affinity to HDAC2 in human MDA-MB-231 cells assessed as increase in thermal stability at 10 uM measured at 6 hrs by CETSA | Homo sapiens | 1 | ALA4811304 | cell-based format | Scientific Literature | |
13. | ALA4813546 | Binding | Binding affinity to HDAC3 in human MDA-MB-231 cells assessed as increase in thermal stability at 10 uM measured at 6 hrs by CETSA | Homo sapiens | 1 | ALA4811304 | cell-based format | Scientific Literature | |
14. | ALA4813547 | Binding | Binding affinity to HDAC6 in human MDA-MB-231 cells assessed as increase in thermal stability at 10 uM measured at 6 hrs by CETSA | Homo sapiens | 1 | ALA4811304 | cell-based format | Scientific Literature | |
15. | ALA4813548 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of clone formation at 2.5 to 10 uM | Homo sapiens | 1 | ALA4811304 | cell-based format | Scientific Literature | |
16. | ALA4813549 | Binding | Inhibition of HDAC1 (unknown origin) | Homo sapiens | 1 | ALA4811304 | single protein format | Scientific Literature | |
17. | ALA4813550 | Binding | Inhibition of HDAC2 (unknown origin) | Homo sapiens | 1 | ALA4811304 | single protein format | Scientific Literature | |
18. | ALA4813551 | Binding | Inhibition of HDAC3 (unknown origin) | Homo sapiens | 1 | ALA4811304 | single protein format | Scientific Literature | |
19. | ALA4813552 | Binding | Inhibition of HDAC6 in human MDA-MB-231 cells assessed as accumulation of acetylated tubulin at 5 to 20 uM by Western blot analysis | Homo sapiens | 1 | ALA4811304 | cell-based format | Scientific Literature | |
20. | ALA4813553 | Binding | Inhibition of HDAC6 in human MDA-MB-231 cells assessed as increase in acetylated lysine at 5 to 20 uM by Western blot analysis | Homo sapiens | 1 | ALA4811304 | cell-based format | Scientific Literature |