# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4827352 | B | Antagonist activity at estrogen receptor in human T47D cells incubated for 18 hrs by ultra high sensitivity luminescence reporter gene assay | Homo sapiens | 42 | ALA4825708 | cell-based format | Scientific Literature | |
2. | ALA4827353 | B | Induction of estrogen receptor degradation in human MCF7 cells incubated for 4 hrs by Alexafluor -488 conjugate anti-mouse IgG staining based fluorescence method | Homo sapiens | 42 | ALA4825708 | cell-based format | Scientific Literature | |
3. | ALA4827354 | B | Induction of estrogen receptor degradation in human MCF7 cells at 0.0002 to 100 nM incubated for 4 hrs by Alexafluor-488 conjugate anti-mouse IgG staining based fluorescence method relative to control | Homo sapiens | 41 | ALA4825708 | cell-based format | Scientific Literature | |
4. | ALA4827355 | F | Antiproliferative activity against human MCF-7 cells incubated for 72 hrs by Cell-titer Glo assay | Homo sapiens | 42 | ALA4825708 | cell-based format | Scientific Literature | |
5. | ALA4827356 | P | Kinetic solubility of compound at pH 7.4 | 42 | ALA4825708 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4827364 | A | Intrinsic clearance in human liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured up to 60 mins by LC-MS/MS analysis | Homo sapiens | 36 | ALA4825708 | microsome format | Scientific Literature | |
7. | ALA4827365 | A | Intrinsic clearance in rat liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured up to 60 mins by LC-MS/MS analysis | Rattus norvegicus | 36 | ALA4825708 | microsome format | Scientific Literature |