| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4840817 | B | Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and measured after 30 minutes | Chlamydia trachomatis | 14 | single protein format | Scientific Literature | ||
| 2. | ALA4840818 | B | Inhibition of human neutrophil elastase using methoxysuccinyl-Ala-Ala-Pro-Val-pNA as substrate incubated for 15 min | Homo sapiens | 16 | tissue-based format | Scientific Literature | ||
| 3. | ALA4840819 | B | Ratio of JO146 IC50 to test compound IC50 for inhibition of recombinant ctHtrA serine protease using Me0Coum-ENLHLPLPI1F-D as substrate pretreated for 10 minutes followed by substrate addition and measured after 30 minutes | Chlamydia trachomatis | 15 | single protein format | Scientific Literature | ||
| 4. | ALA4840820 | B | Ratio of JO146 IC50 to test compound IC50 for inhibition of human neutrophil elastase using methoxysuccinyl-Ala-Ala-Pro-Val-pNA as substrate incubated for 15 min | Homo sapiens | 16 | tissue-based format | Scientific Literature | ||
| 5. | ALA4840821 | F | Antibacterial activity against Chlamydia trachomatis D (D/UW-3/Cx; CtD) infected in HEp-2 cells assessed as log reduction in infectivity unit at 25 uM measured after 44 hrs | Chlamydia trachomatis | 10 | organism-based format | Scientific Literature | ||
| 6. | ALA4840822 | F | Antibacterial activity against Chlamydia pecorum G (MC/MarsBar;CpG) infected in McCoy B cells assessed as log reduction in infectivity unit at 25 uM measured after 44 hrs | Chlamydia pecorum | 8 | organism-based format | Scientific Literature | ||
| 7. | ALA4840823 | A | Cytotoxicity against human HEp-2 cells assessed as reduction in MTS absorbance at 100 uM by MTS assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 8. | ALA4840828 | F | Antibacterial activity against Chlamydia trachomatis D (D/UW-3/Cx; CtD) infected in HEp-2 cells assessed as reduction in bacterial titer at 50 to 100 uM measured after 44 hrs | Chlamydia trachomatis | 4 | organism-based format | Scientific Literature | ||
| 9. | ALA4840829 | F | Antibacterial activity against Chlamydia pecorum G (MC/MarsBar;CpG) infected in McCoy B cells assessed as reduction in bacterial titer at 50 to 100 uM measured after 44 hrs | Chlamydia pecorum | 4 | organism-based format | Scientific Literature |
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