# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4804300 | F | Upregulation of YAP1 protein level in human NCI-H929 cells at 1 to 10 uM measured after 16 hrs by Western blot analysis | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
2. | ALA4804301 | F | Upregulation of YAP1 protein level in human MM1.S cells at 1 to 10 uM measured after 16 hrs by Western blot analysis | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
3. | ALA4804305 | F | Downregulation of phosphorylated-MOB1 protein level in human MM1.S cells at 1 to 10 uM measured after 6 hrs by Western blot analysis | Homo sapiens | 7 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
4. | ALA4804306 | B | Inhibition of STK4 (unknown origin) using fluorescein-labelled Ser/Thr-07 peptide as substrate incubated for 1 hr in presence of ATP at Km concentration by Z-LYTE assay | Homo sapiens | 59 | ALA4804281 | single protein format | Patent Bioactivity Data | |
5. | ALA4804307 | B | Inhibition of MST4 (unknown origin) using fluorescein-labelled Ser/Thr-07 peptide as substrate incubated for 1 hr in presence of ATP at Km concentration by Z-LYTE assay | Homo sapiens | 1 | ALA4804281 | single protein format | Patent Bioactivity Data | |
6. | ALA4804308 | B | Inhibition of STK3 (unknown origin) using fluorescein-labelled Ser/Thr-07 peptide as substrate incubated for 1 hr in presence of ATP at Km concentration by Z-LYTE assay | Homo sapiens | 11 | ALA4804281 | single protein format | Patent Bioactivity Data | |
7. | ALA4804309 | B | Inhibition of STK24 (unknown origin) using fluorescein-labelled Ser/Thr-07 peptide as substrate incubated for 1 hr in presence of ATP at Km concentration by Z-LYTE assay | Homo sapiens | 12 | ALA4804281 | single protein format | Patent Bioactivity Data | |
8. | ALA4804310 | B | Inhibition of wild-type human full length CSNK1G3 (M1 to K447 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4804281 | assay format | Patent Bioactivity Data | |
9. | ALA4804311 | B | Inhibition of wild-type human partial length DYRK1A (H129 to S509 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4804281 | assay format | Patent Bioactivity Data | |
10. | ALA4804312 | B | Inhibition of wild-type human full length GSK3A (M1 to S483 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4804281 | assay format | Patent Bioactivity Data | |
11. | ALA4804313 | B | Inhibition of wild-type human partial length CIT (M68 to E432 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4804281 | assay format | Patent Bioactivity Data | |
12. | ALA4804314 | B | Inhibition of wild-type human full length CSNK1E (M1 to K416 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4804281 | assay format | Patent Bioactivity Data | |
13. | ALA4804315 | B | Inhibition of wild-type human partial length DRAK1 (R32 to E363 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4804281 | assay format | Patent Bioactivity Data | |
14. | ALA4804316 | B | Inhibition of wild-type human partial length BMPR1B (D178 to L502 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4804281 | assay format | Patent Bioactivity Data | |
15. | ALA4804317 | B | Inhibition of wild-type human full length DYRK1B (M1 to S629 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4804281 | assay format | Patent Bioactivity Data | |
16. | ALA4804318 | B | Inhibition of wild-type human partial length MST2 (D17 to E318 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4804281 | assay format | Patent Bioactivity Data | |
17. | ALA4804319 | B | Inhibition of wild-type human full length CLK1 (M1 to I484 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4804281 | assay format | Patent Bioactivity Data | |
18. | ALA4804320 | B | Inhibition of wild-type human full length CSNK1A1L (M1 to N337 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4804281 | assay format | Patent Bioactivity Data | |
19. | ALA4804321 | B | Inhibition of wild-type human partial length VRK2 (M1 to T336 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4804281 | assay format | Patent Bioactivity Data | |
20. | ALA4804322 | B | Inhibition of wild-type human partial length DCAMKL3 (E140 to V628 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4804281 | assay format | Patent Bioactivity Data |