# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4808435 | Binding | Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellular target engagement assay | Homo sapiens | 33 | ALA4808168 | single protein format | Scientific Literature | |
2. | ALA4808436 | Functional | Antiproliferative activity against human Z138 cells incubated for 10 days by cell titer-glo assay | Homo sapiens | 33 | ALA4808168 | cell-based format | Scientific Literature | |
3. | ALA4808437 | ADME | Plasma clearance in rat | Rattus norvegicus | 28 | ALA4808168 | assay format | Scientific Literature | |
4. | ALA4808438 | ADME | Unbound clearance in rat | Rattus norvegicus | 28 | ALA4808168 | assay format | Scientific Literature | |
5. | ALA4808439 | ADME | Unbound volume of distribution in rat | Rattus norvegicus | 28 | ALA4808168 | assay format | Scientific Literature | |
6. | ALA4808440 | ADME | MRT in rat | Rattus norvegicus | 28 | ALA4808168 | assay format | Scientific Literature | |
7. | ALA4808441 | ADME | Oral bioavailability in rat | Rattus norvegicus | 24 | ALA4808168 | organism-based format | Scientific Literature | |
8. | ALA4808442 | Physicochemical | Solubility of the compound in FaSSIF at pH 2 at 200 uM incubated for 24 hrs by UV-vis detection based HPLC analysis | 27 | ALA4808168 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA4808443 | Physicochemical | Solubility of the compound in FaSSIF at pH 7 at 200 uM incubated for 24 hrs by UV-vis detection based HPLC analysis | 27 | ALA4808168 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA4808444 | Physicochemical | Lipophilicity, logD of compound at pH 7 by UV-vis detection based HPLC analysis | 27 | ALA4808168 | small-molecule physicochemical format | Scientific Literature |