| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4843795 | ADME | Inhibition of recombinant human CYP3A4 expressed in Escherichia coli using VG as probe substrate incubated for 15 to 60 mins by fluorometric assay | Homo sapiens | 5 | ALA4842350 | assay format | Scientific Literature | |
| 2. | ALA4843798 | Binding | Inhibition of BRD4 in human PBMC assessed as reduction in LPS-induced IL-6 secretion incubated for 18 to 24 hrs by MSD assay | Homo sapiens | 34 | ALA4842350 | tissue-based format | Scientific Literature | |
| 3. | ALA4843799 | Binding | Inhibition of BRD4 in human whole blood assessed as reduction in LPS-induced IL-6 secretion preincubated for 30 mins followed by LPS stimulation and measured after 24 hrs by MSD assay | Homo sapiens | 11 | ALA4842350 | tissue-based format | Scientific Literature | |
| 4. | ALA4843801 | ADME | Inhibition of recombinant human CYP2C9 expressed in Escherichia coli using FCA as substrate incubated for 15 to 60 mins by fluorometric assay | Homo sapiens | 6 | ALA4842350 | assay format | Scientific Literature | |
| 5. | ALA4843806 | Binding | Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal 6His-tagged BRD4-BD1 Y390A mutant (1 to 477 residue) expressed in Escherichia coli incubated for 30 mins by TR-FRET assay | Homo sapiens | 33 | ALA4842350 | assay format | Scientific Literature |
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