# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4815949 | Functional | Induction of cell sensitization to imatinib in imatinib-resistant human K562 cells assessed as cell death at 5 uM incubated for 72 hrs in presence of 1 uM imatinib by PI staining based flow cytometry (Rvb = 19%) | Homo sapiens | 18 | ALA4813967 | cell-based format | Scientific Literature | |
2. | ALA4815950 | ADME | Cytotoxicity against human HS5 cells assessed as cell death at 5 uM incubated for 72 hrs by PI staining based flow cytometry | Homo sapiens | 16 | ALA4813967 | cell-based format | Scientific Literature | |
3. | ALA4815951 | ADME | Cytotoxicity against African green monkey COS7 cells assessed as cell viability at 10 uM incubated for 72 hrs by MTT assay | Chlorocebus aethiops | 16 | ALA4813967 | cell-based format | Scientific Literature | |
4. | ALA4815954 | ADME | Agonist activity at Gal4-fused human PPARgamma transfected in African green monkey COS7 cells co-transfected with pGal5-TK-pGL3 and pRenilla-CMV assessed as receptor transactivation at 10 uM incubated for 39 hrs by dual luciferase reporter gene assay relative to piaglitazone | Homo sapiens | 17 | ALA4813967 | cell-based format | Scientific Literature | |
5. | ALA4815956 | ADME | Cytotoxicity against imatinib-resistant human K562 cells assessed as cell death at 5 uM incubated for 72 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 16 | ALA4813967 | cell-based format | Scientific Literature | |
6. | ALA4815957 | ADME | Cytotoxicity against human HS5 cells assessed as cell death at 5 uM incubated for 72 hrs in presence of imatinib by PI staining based flow cytometry | Homo sapiens | 16 | ALA4813967 | cell-based format | Scientific Literature | |
7. | ALA4815958 | ADME | Cytotoxicity against African green monkey COS7 cells assessed as cell viability at 10 uM incubated for 72 hrs in presence of imatinib by MTT assay | Chlorocebus aethiops | 16 | ALA4813967 | cell-based format | Scientific Literature |