# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4839945 | Binding | Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate at 10 uM by fluorescent assay relative to DMSO | Homo sapiens | 40 | ALA4837260 | single protein format | Scientific Literature | |
2. | ALA4839946 | Binding | Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assay | Homo sapiens | 30 | ALA4837260 | single protein format | Scientific Literature | |
3. | ALA4839947 | Binding | Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assay relative to 2-butylbenzofuran-3-yl)(3,5-diiodo-4-(3-(pyrrolidin-1-yl-propoxy)pheny)methanone | Homo sapiens | 30 | ALA4837260 | single protein format | Scientific Literature | |
4. | ALA4839948 | Functional | Antiproliferative activity against human HL-60 cells measured after 24 hrs by MTT assay | Homo sapiens | 40 | ALA4837260 | cell-based format | Scientific Literature | |
5. | ALA4839949 | Functional | Antiproliferative activity against human U-937 cells measured after 24 hrs by MTT assay | Homo sapiens | 40 | ALA4837260 | cell-based format | Scientific Literature | |
6. | ALA4839950 | Functional | Antiproliferative activity against human MCF7 cells measured after 24 hrs by MTT assay | Homo sapiens | 40 | ALA4837260 | cell-based format | Scientific Literature | |
7. | ALA4839951 | Functional | Antiproliferative activity against human MDA-MB-231 cells measured after 24 hrs by MTT assay | Homo sapiens | 42 | ALA4837260 | cell-based format | Scientific Literature |