| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4822136 | F | Cytotoxicity activity against human HeLa cells assessed as cell killing at 10 uM measured after 24 hrs by CellTiter Glo luminescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4822137 | B | Protac activity at CRBN/eIF4E in human HEK293T cells assessed as induction of intracellular eIF4E degradation at 0.1 to 10 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA4822138 | B | Protac activity at CRBN/eIF4E in human HEK293T cells assessed as induction of intracellular eIF4E degradation at 1 uM measured after 0.5 to 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4822139 | B | Protac activity at CRBN/eIF4E in human HEK293T cells assessed as induction of eIF4E ubiquitination at 1 uM in presence of 26S proteasome inhibitor, Bortezomib by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4822145 | B | Binding affinity to 15N-labeled-GB1-eIF4E (unknown origin) at 50 to 300 uM measured by NMR analysis | Homo sapiens | 2 | single protein format | Scientific Literature |
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