# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4819966 | Binding | Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in presence of ATP by ADP-Glo kinase assay | Homo sapiens | 29 | ALA4819005 | assay format | Scientific Literature | |
2. | ALA4819967 | Functional | Antiproliferative activity against human HT-29 cells assessed as inhibition of VEGF-induced cell proliferation measured after 24 hrs by CCK8 assay | Homo sapiens | 29 | ALA4819005 | cell-based format | Scientific Literature | |
3. | ALA4819968 | Functional | Antiproliferative activity against human MKN-45 cells assessed assessed as inhibition of VEGF-induced cell proliferation measured after 24 hrs by CCK8 assay | Homo sapiens | 29 | ALA4819005 | cell-based format | Scientific Literature | |
4. | ALA4819969 | ADME | Cytotoxicity against HUVEC cells assessed as inhibition of cell proliferation in presence of VEGF measured after 24 hrs by CCK8 assay | Homo sapiens | 29 | ALA4819005 | cell-based format | Scientific Literature | |
5. | ALA4819970 | Functional | Anti-angiogenesis activity against HUVEC cells assessed as inhibition of cell migration measured after 24 hrs by Transwell assay | Homo sapiens | 1 | ALA4819005 | cell-based format | Scientific Literature | |
6. | ALA4819971 | Functional | Anti-angiogenesis activity against HUVEC cells assessed as inhibition of tube formation at 0.2 to 0.8 uM measured after 6 hrs by microscopic method | Homo sapiens | 1 | ALA4819005 | cell-based format | Scientific Literature | |
7. | ALA4819972 | Binding | Inhibition of VEGFR2 phosphorylation in HUVEC cells at 0.2 to 0.8 uM measured after 24 hrs by Western blot assay | Homo sapiens | 1 | ALA4819005 | cell-based format | Scientific Literature | |
8. | ALA4819973 | Functional | Anti-angiogenesis activity against Zebra fish assessed as inhibition of internodal vascular angiogenesis at 40 mg/L measured after 24 hrs by microscopic method | Danio rerio | 1 | ALA4819005 | organism-based format | Scientific Literature | |
9. | ALA4819974 | Functional | Anti-angiogenesis activity against Zebra fish assessed as inhibition of internodal vascular regeneration at 20 mg/L measured after 24 hrs by microscopic method | Danio rerio | 1 | ALA4819005 | organism-based format | Scientific Literature |