# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4829859 | Binding | Inhibition of human recombinant Cathepsin C using H-Gly-Arg-AMC as substrate pretreated for 30 mins followed by substrate addition incubated for 60 mins | Homo sapiens | 74 | ALA4828733 | single protein format | Scientific Literature | |
2. | ALA4829860 | Binding | Inhibition of human Cathepsin C in human THP-1 cells using H-Gly-Phe-AFC as substrate pretreated for 60 mins followed by substrate addition incubated for 60 mins | Homo sapiens | 74 | ALA4828733 | cell-based format | Scientific Literature | |
3. | ALA4829861 | Binding | Inhibition of human Cathepsin C in human U-937 cells using H-Gly-Phe-AFC as substrate pretreated for 60 mins followed by substrate addition incubated for 60 mins | Homo sapiens | 74 | ALA4828733 | cell-based format | Scientific Literature | |
4. | ALA4829862 | ADME | Cytotoxicity against human L02 cells assessed as cell viability incubated for 48 hrs by CCK-8 assay | Homo sapiens | 74 | ALA4828733 | cell-based format | Scientific Literature | |
5. | ALA5165027 | Binding | Inhibition of human recombinant Cathepsin C using H-Gly-Arg-AMC as substrate pretreated for 30 mins followed by substrate addition and incubated for 60 mins by microplate reader assay | Homo sapiens | 47 | ALA5154871 | single protein format | Scientific Literature | |
6. | ALA5165028 | Binding | Inhibition of Cathepsin C in human THP-1 cells using H-Gly-Phe-AFC as substrate pretreated for 1 hr followed by substrate addition and incubated for 60 mins by microplate reader assay | Homo sapiens | 45 | ALA5154871 | cell-based format | Scientific Literature | |
7. | ALA5165029 | Binding | Inhibition of Cathepsin C in human U-937 cells using H-Gly-Phe-AFC as substrate pretreated for 1 hr followed by substrate addition and incubated for 60 mins by microplate reader assay | Homo sapiens | 45 | ALA5154871 | cell-based format | Scientific Literature |