# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4825059 | Functional | Cytotoxicity against human BT-474 cells assessed as cell growth inhibition by MTT assay | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
2. | ALA4825060 | Functional | Induction of apoptosis in human BT-474 cells assessed as reduced number of viable cells at 0.25 to 1 uM by phase-contrast microscopy | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
3. | ALA4825061 | Functional | Induction of apoptosis in human BT-474 cells assessed as cell wall deformation at 0.25 to 1 uM by phase-contrast microscopy | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
4. | ALA4825062 | Functional | Induction of apoptosis in human BT-474 cells assessed as cell shrinkage at 0.25 to 1 uM by phase-contrast microscopy | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
5. | ALA4825063 | Functional | Induction of apoptosis in human BT-474 cells assessed as cellular morphological changes at 0.25 to 1 uM incubated for 24 hrs by AO/EB staining assay | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
6. | ALA4825064 | Functional | Induction of apoptosis in human BT-474 cells assessed as horseshoe-shaped nuclei by measuring bright clue colour at 0.25 to 1 uM incubated for 24 hrs by DAPI staining based fluorescence microscope assay | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
7. | ALA4825065 | Functional | Induction of apoptosis in human BT-474 cells assessed as nuclear shrinkage by measuring bright clue colour at 0.25 to 1 uM incubated for 24 hrs by DAPI staining based fluorescence microscope assay | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
8. | ALA4825066 | Functional | Induction of apoptosis in human BT-474 cells assessed as fragmented nucleus by measuring bright clue colour at 0.25 to 1 uM incubated for 24 hrs by DAPI staining based fluorescence microscope assay | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
9. | ALA4825067 | Functional | Induction of apoptosis in human BT-474 cells assessed as pyknotic and chromatin condensation by measuring bright clue colour at 0.25 to 1 uM incubated for 24 hrs by DAPI staining based fluorescence microscope assay | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
10. | ALA4825068 | Functional | Inhibition of colony formation in human BT-474 cells by clonogenic assay | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
11. | ALA4825069 | Functional | Induction of apoptosis in human BT-474 cells assessed as viable cells at 0.5 uM incubated for 24 hrs by annexin-V/FITC-PI staining assay (Rvb = 88.49%) | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
12. | ALA4825070 | Functional | Induction of apoptosis in human BT-474 cells assessed as early apoptotic cells at 0.5 uM incubated for 24 hrs by annexin-V/FITC-PI staining assay (Rvb = 9.44%) | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
13. | ALA4825071 | Functional | Induction of apoptosis in human BT-474 cells assessed as late apoptotic cells at 0.5 uM incubated for 24 hrs by annexin-V/FITC-PI staining assay (Rvb = 1.83%) | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
14. | ALA4825072 | Functional | Induction of apoptosis in human BT-474 cells assessed as necrotic cells at 0.5 uM incubated for 24 hrs by annexin-V/FITC-PI staining assay (Rvb = 0.24%) | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
15. | ALA4825073 | Functional | Induction of apoptosis in human BT-474 cells assessed as viable cells at 1 uM incubated for 24 hrs by annexin-V/FITC-PI staining assay (Rvb = 88.49%) | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
16. | ALA4825074 | Functional | Induction of apoptosis in human BT-474 cells assessed as early apoptotic cells at 1 uM incubated for 24 hrs by annexin-V/FITC-PI staining assay (Rvb = 9.44%) | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
17. | ALA4825075 | Functional | Induction of apoptosis in human BT-474 cells assessed as late apoptotic cells at 1 uM incubated for 24 hrs by annexin-V/FITC-PI staining assay (Rvb = 1.83%) | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
18. | ALA4825076 | Functional | Induction of apoptosis in human BT-474 cells assessed as necrotic cells at 1 uM incubated for 24 hrs by annexin-V/FITC-PI staining assay (Rvb = 0.24%) | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
19. | ALA4825077 | Functional | Induction of mitochondrial membrane potential loss in human BT-474 cells assessed as polarised cells at 0.25 uM incubated for 24 hrs by JC11 staining based assay (Rvb = 93.95%) | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature | |
20. | ALA4825078 | Functional | Induction of mitochondrial membrane potential loss in human BT-474 cells assessed as polarised cells at 0.5 uM incubated for 24 hrs by JC11 staining based assay (Rvb = 93.95%) | Homo sapiens | 1 | ALA4823299 | cell-based format | Scientific Literature |