# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4833899 | A | Cytotoxicity against mouse primary peritoneal macrophages measured after 3 days by resazurin staining based fluorometric analysis | Mus musculus | 31 | cell-based format | Scientific Literature | ||
2. | ALA4833900 | F | Antileishmanial activity against amastigote stage of Leishmania infantum MHOM/MA(BE)/67/ITMAP263 infected in mouse peritoneal macrophage assessed as reduction in parasite burden incubated for 5 days by Giemsa staining based microscopic analysis | Leishmania infantum | 31 | organism-based format | Scientific Literature | ||
3. | ALA4833911 | A | Cytotoxicity against human MRC5 cells measured after 3 days by resazurin staining based fluorometric analysis | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
4. | ALA4833912 | T | Selectivity index, ratio of CC50 for human MRC5 cells to EC50 for Leishmania infantum MHOM/MA(BE)/67/ITMAP263 | 30 | assay format | Scientific Literature | |||
5. | ALA4833913 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance at 1 uM measured upto 120 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Homo sapiens | 30 | microsome format | Scientific Literature | ||
6. | ALA4833914 | A | Metabolic stability in golden hamster liver microsomes assessed as intrinsic clearance at 1 uM measured upto 120 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Mesocricetus auratus | 30 | microsome format | Scientific Literature |