# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4839698 | Binding | Inhibition of human recombinant ARG1 expressed in Escherichia coli using thioarginine as a substrate preincubated for 30 mins followed by substrate addition and incubated for 60 mins by fluorescence based arginine thio ornithine generating assay | Homo sapiens | 31 | ALA4837253 | assay format | Scientific Literature | |
2. | ALA4839699 | ADME | Oral bioavailability in C57BL/6 mouse at 10 mg/kg | Mus musculus | 22 | ALA4837253 | organism-based format | Scientific Literature | |
3. | ALA4839702 | ADME | Stability in C57BL/6 mouse hepatocytes | Mus musculus | 2 | ALA4837253 | cell-based format | Scientific Literature | |
4. | ALA4839703 | ADME | Oral bioavailability in C57BL/6 mouse in the presence of compound 18 at 10 mg/kg | Mus musculus | 1 | ALA4837253 | organism-based format | Scientific Literature | |
5. | ALA4839714 | ADME | Metabolic stability in C57BL/6 mouse hepatocytes assessed as hydrolysis product of (2S,3R,4R)-4-amino-3-(3-boronopropyl)pyrrolidine-2-carboxylic acid measured | Mus musculus | 1 | ALA4837253 | cell-based format | Scientific Literature |