# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4835698 | F | Antiproliferative activity against human RS4-11 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
2. | ALA4835699 | B | Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation at 0.1 to 1 uM incubated for 6 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4835700 | B | Molecular glue activity at CRBN/MDM2/p53 in human RS4-11 cells assessed as induction of p53 degradation at 0.1 to 1 uM incubated for 6 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4835701 | B | Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation at 100 nM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA4835702 | B | Molecular glue activity at CRBN/MDM2/p53 in human RS4-11 cells assessed as induction of p53 degradation at 100 nM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4835703 | B | Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation at 100 nM incubated for 4 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA4835704 | B | Molecular glue activity at CRBN/MDM2/p53 in human RS4-11 cells assessed as induction of p53 degradation at 100 nM incubated for 4 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA4835705 | B | Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation at 100 nM incubated for 8 hrs by western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA4835706 | B | Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation incubated for 12 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4835707 | B | Molecular glue activity at CRBN/MDM2/p53 in human RS4-11 cells assessed as induction of p53 degradation incubated for 12 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA4835708 | B | Molecular glue activity at CRBN/MDM2 in human MV4-11 cells harboring wild type TP53 assessed as induction of MDM2 degradation by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4835709 | B | Molecular glue activity at CRBN/MDM2 in human MOLM-13 cells harboring wild type TP53 assessed as induction of MDM2 degradation by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA4835710 | B | Molecular glue activity at CRBN/MDM2 in human MOLT-4 cells harboring wild type TP53 assessed as induction of MDM2 degradation by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA4835711 | B | Molecular glue activity at CRBN/MDM2 in human CCRF-CEM cells harboring mutant TP53 assessed as induction of MDM2 degradation by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA4835712 | B | Molecular glue activity at CRBN/MDM2 in human NOMO-1 cells harboring mutant TP53 assessed as induction of MDM2 degradation by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA4835713 | B | Molecular glue activity at CRBN/MDM2 in human A549 cells assessed as induction of MDM2 degradation by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA4835714 | B | Molecular glue activity at CRBN/MDM2 in human HepG2 cells assessed as induction of MDM2 degradation by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA4835715 | B | Molecular glue activity at CRBN/MDM2 in human WM-115 cells assessed as induction of MDM2 degradation by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4835716 | B | Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation at 100 nM pretreated with CRBN ligand, lenalidomide for 1 hr followed by incubation with compound for 6 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA4835717 | B | Molecular glue activity at CRBN/MDM2/p53 in human RS4-11 cells assessed as induction of p53 degradation at 100 nM pretreated with CRBN ligand, lenalidomide for 1 hr followed by incubation with compound for 6 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |