# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4823991 | Functional | Antiviral activity against RSV A2 infected in HEp-2 cells assessed as reduction in virus-induced cytopathic effect after 4 days by CellTiter Glo viability assay | Human respiratory syncytial virus | 26 | ALA4823256 | organism-based format | Scientific Literature | |
2. | ALA4823992 | ADME | Cytotoxicity against human HEp-2 cells assessed as reduction in cell viability incubated for 4 to 5 days by CellTiter Glo viability assay | Homo sapiens | 26 | ALA4823256 | cell-based format | Scientific Literature | |
3. | ALA4823996 | Physicochemical | Lipophilicity, log D of compound in acetonitrile and water shaken for 30 mins by HPLC/UV analysis | 21 | ALA4823256 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4823997 | ADME | Permeability across apical to basolateral side in human Caco-2 cells | Homo sapiens | 5 | ALA4823256 | cell-based format | Scientific Literature | |
5. | ALA4823998 | ADME | Permeability across basolateral to apical side in human Caco-2 cells | Homo sapiens | 5 | ALA4823256 | cell-based format | Scientific Literature | |
6. | ALA4823999 | ADME | Oral bioavailability in Sprague-Dawley rat at 8 mg/kg by LC-MS/MS method | Rattus norvegicus | 2 | ALA4823256 | organism-based format | Scientific Literature | |
7. | ALA4824001 | ADME | Oral bioavailability in cynomolgus monkey at 20 mg/kg by LC-MS/MS method | Macaca fascicularis | 3 | ALA4823256 | organism-based format | Scientific Literature |