#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4808258	Binding	Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells at 10 uM incubated for 24 hrs by quanti-blue SEAP reporter gene assay relative to control	Homo sapiens	25	ALA4808161	cell-based format	Scientific Literature
2.	ALA4808259	Binding	Activation of mouse STING expressed in RAW-Lucia ISG cells at 50 uM incubated for 24 hrs by quanti-blue SEAP reporter gene assay relative to control	Mus musculus	25	ALA4808161	cell-based format	Scientific Literature
3.	ALA4808260	Binding	Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assay	Homo sapiens	13	ALA4808161	cell-based format	Scientific Literature
4.	ALA4808261	Binding	Activation of mouse STING expressed in RAW-Lucia ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assay	Mus musculus	13	ALA4808161	cell-based format	Scientific Literature
5.	ALA4808262	ADME	Half life in rat at 1 mg/kg, iv	Rattus norvegicus	2	ALA4808161	organism-based format	Scientific Literature
6.	ALA4808263	ADME	AUClast in rat at 1 mg/kg, iv	Rattus norvegicus	2	ALA4808161	organism-based format	Scientific Literature
7.	ALA4808264	ADME	Observed AUCinfinity in rat at 1 mg/kg, iv	Rattus norvegicus	2	ALA4808161	organism-based format	Scientific Literature
8.	ALA4808265	ADME	Observed clearance in rat at 1 mg/kg, iv	Rattus norvegicus	2	ALA4808161	organism-based format	Scientific Literature
9.	ALA4808266	ADME	Observed MRT infinity in rat at 1 mg/kg, iv	Rattus norvegicus	2	ALA4808161	organism-based format	Scientific Literature
10.	ALA4808267	ADME	Observed volume of distribution at steady state in rat at 1 mg/kg, iv	Rattus norvegicus	2	ALA4808161	organism-based format	Scientific Literature
11.	ALA4808270	Binding	Activation of STING in human THP1-Dual cells assessed as induction of ISG signaling measured after 24 hrs by Quanti-Blue reagent based assay	Homo sapiens	1	ALA4808161	cell-based format	Scientific Literature
12.	ALA4808271	Binding	Activation of STING in human THP1-Dual cells assessed as induction of NF-KB signaling measured after 24 hrs by Quanti-Blue reagent based assay	Homo sapiens	1	ALA4808161	cell-based format	Scientific Literature
13.	ALA4808274	Binding	Activation of STING in human THP1-Dual cells assessed as increase in IP-10 secretion at 0.01 to 10 uM measured after 24 hrs by ELISA	Homo sapiens	2	ALA4808161	cell-based format	Scientific Literature
14.	ALA4808275	Binding	Activation of STING in human THP1-Dual cells assessed as increase in IFNbeta secretion at 10 uM measured after 24 hrs by ELISA	Homo sapiens	2	ALA4808161	cell-based format	Scientific Literature
15.	ALA4808276	Binding	Activation of STING in human THP1-Dual cells assessed as increase in TBK1/IRF3 phosphorylation measured after 4 hrs by Western blot analysis	Homo sapiens	2	ALA4808161	cell-based format	Scientific Literature
16.	ALA4808277	Functional	Effect on ISG expression in human THP1-Dual KO-STING cells at 10 uM measured after 24 hrs	Homo sapiens	1	ALA4808161	tissue-based format	Scientific Literature
17.	ALA4808278	Binding	Binding affinity to human STING R232 mutant assessed as thermal stability by measuring melting temperature after 24 hrs differential scanning fluorimetry (Rvb = 38.75 degreeC)	Homo sapiens	2	ALA4808161	assay format	Scientific Literature
18.	ALA4808279	Binding	Binding affinity to human STING H232 mutant assessed as thermal stability by measuring melting temperature after 24 hrs differential scanning fluorimetry (Rvb = 39.5 degreeC)	Homo sapiens	2	ALA4808161	assay format	Scientific Literature
19.	ALA4808280	Binding	Binding affinity to human STING 293Q mutant assessed as thermal stability by measuring melting temperature after 24 hrs differential scanning fluorimetry (Rvb = 46.25 degreeC)	Homo sapiens	2	ALA4808161	assay format	Scientific Literature
20.	ALA4808281	Binding	Binding affinity to human STING HAQ mutant assessed as thermal stability by measuring melting temperature after 24 hrs differential scanning fluorimetry (Rvb = 37.25 degreeC)	Homo sapiens	2	ALA4808161	assay format	Scientific Literature