| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4825887 | F | Antiviral activity against Respiratory syncytial virus A2 infected in African green monkey Vero cells by Plaque reduction assay | Human respiratory syncytial virus | 21 | organism-based format | Scientific Literature | ||
| 2. | ALA4825888 | A | Cytotoxicity against African green monkey Vero cells by MTT assay | Chlorocebus sabaeus | 17 | cell-based format | Scientific Literature | ||
| 3. | ALA4825891 | A | Protein binding in rat plasma assessed as unbound fraction at 5 uM by LC-MS/MS analysis based equilibrium dialysis method | Rattus norvegicus | 12 | cell-free format | Scientific Literature | ||
| 4. | ALA4825892 | A | Protein binding in dog plasma assessed as unbound fraction at 5 uM by LC-MS/MS analysis based equilibrium dialysis method | Canis lupus familiaris | 12 | cell-free format | Scientific Literature | ||
| 5. | ALA4825893 | A | Protein binding in human plasma assessed as unbound fraction at 5 uM by LC-MS/MS analysis based equilibrium dialysis method | Homo sapiens | 12 | cell-free format | Scientific Literature | ||
| 6. | ALA4825894 | A | Intrinsic clearance in Sprague-Dawley rat liver microsomes preincubated followed by NADPH addition and measured up to 45 mins by LC-MS/MS analysis | Rattus norvegicus | 12 | microsome format | Scientific Literature | ||
| 7. | ALA4825895 | A | Intrinsic clearance in Beagle dog liver microsomes preincubated followed by NADPH addition and measured up to 45 mins by LC-MS/MS analysis | Canis lupus familiaris | 12 | microsome format | Scientific Literature | ||
| 8. | ALA4825896 | A | Intrinsic clearance in human liver microsomes preincubated followed by NADPH addition and measured up to 45 mins by LC-MS/MS analysis | Homo sapiens | 12 | microsome format | Scientific Literature | ||
| 9. | ALA4825897 | A | Half life in Sprague-Dawley rat liver microsomes preincubated followed by NADPH addition and measured up to 45 mins by LC-MS/MS analysis | Rattus norvegicus | 9 | microsome format | Scientific Literature | ||
| 10. | ALA4825898 | A | Half life in Beagle dog liver microsomes preincubated followed by NADPH addition and measured up to 45 mins by LC-MS/MS analysis | Canis lupus familiaris | 9 | microsome format | Scientific Literature | ||
| 11. | ALA4825899 | A | Half life in human liver microsomes preincubated followed by NADPH addition and measured up to 45 mins by LC-MS/MS analysis | Homo sapiens | 9 | microsome format | Scientific Literature | ||
| 12. | ALA4825906 | B | Inhibition of Respiratory syncytial virus A2 fusion protein expressed in HEK293T cells harboring GAL4-NF-kappaB assessed as reduction in cell-cell fusion by luciferase assay | Human respiratory syncytial virus A2 | 24 | cell-based format | Scientific Literature | ||
| 13. | ALA4825907 | P | Thermodynamic solubility in PBS at 1 to 100 uM at pH 7.4 by HPLC-UV method | 11 | small-molecule physicochemical format | Scientific Literature | |||
| 14. | ALA4825908 | A | Apparent permeability across apical to basolateral side in MDCK-MDR1 cells at 10 uM measured at 60 mins by LC-MS/MS analysis | Canis lupus familiaris | 9 | cell-based format | Scientific Literature | ||
| 15. | ALA4825909 | A | Apparent permeability across basolateral side to apical side in MDCK-MDR1 cells at 10 uM measured at 60 mins by LC-MS/MS analysis | Canis lupus familiaris | 9 | cell-based format | Scientific Literature | ||
| 16. | ALA4825910 | A | Efflux ratio of apparent permeability in MDCK-MDR1 cells at 10 uM measured at 60 mins by LC-MS/MS analysis | Canis lupus familiaris | 9 | cell-based format | Scientific Literature | ||
| 17. | ALA4825916 | A | Intrinsic clearance in rat hepatocytes at 3 uM assessed per million cells measured up to 60 mins by LC-MS/MS analysis | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
| 18. | ALA4825917 | A | Intrinsic clearance in Beagle dog hepatocytes at 3 uM assessed per million cells measured up to 60 mins by LC-MS/MS analysis | Canis lupus familiaris | 7 | cell-based format | Scientific Literature | ||
| 19. | ALA4825918 | A | Intrinsic clearance in human hepatocytes at 3 uM assessed per million cells measured up to 60 mins by LC-MS/MS analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 20. | ALA4825919 | A | Half life in rat hepatocytes at 3 uM measured up to 60 mins by LC-MS/MS analysis | Rattus norvegicus | 6 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!